| 9/4/2021 | Assumption | 0 | at | Kutztown (11-2) | 19 | at PSAC | ||
| 9/11/2021 | Bentley (9-2,8-2) | 40 | at | Assumption | 28 | |||
| 9/18/2021 | Pace (2-8,2-7) | 21 | at | Assumption | 32 | |||
| 9/25/2021 | Assumption | 26 | at | Stonehill (8-2,7-2) | 27 | |||
| 10/2/2021 | Assumption | 35 | at | Franklin Pierce (0-10,0-9) | 28 | |||
| 10/8/2021 | Southern Connecticut (4-6,3-6) | 0 | at | Assumption | 26 | |||
| 10/23/2021 | American Int'l (4-6,3-6) | 21 | at | Assumption | 42 | |||
| 10/30/2021 | Assumption | 10 | at | New Haven (10-2,10-0) | 16 | |||
| 11/6/2021 | Saint Anselm (3-6,3-5) | 35 | at | Assumption | 44 | |||
| 11/13/2021 | Assumption | 23 | at | Bentley (9-2,8-2) | 48 |
| vs Assumption | vs Other Opponents | Assumption compared to OOs | |
| Record: | 5-5 | 53-41 | |
| Points Scored: | 25.50 | 25.28 | -0.22 |
| Points Allowed: | 26.60 | 23.17 | 3.43 |
| Margin: | -1.10 | 2.11 | 3.21 |
| Total Points: | 52.10 | 48.45 | 3.65 |