| 9/7/2019 | North Carolina Wesleyan | 31 | at | Emory & Henry (7-3) | 24 | OT | at ODC | |
| 9/14/2019 | Shenandoah (6-4) | 35 | at | North Carolina Wesleyan | 19 | ODC | ||
| 9/28/2019 | North Carolina Wesleyan | 21 | at | Stetson (7-4) | 55 | at Pio | ||
| 10/5/2019 | North Carolina Wesleyan | 52 | at | LaGrange (3-7,1-6) | 35 | |||
| 10/12/2019 | Greensboro (1-9,0-7) | 7 | at | North Carolina Wesleyan | 44 | |||
| 10/19/2019 | North Carolina Wesleyan | 24 | at | Averett (7-3,5-2) | 41 | |||
| 10/26/2019 | Brevard (8-2,5-2) | 26 | at | North Carolina Wesleyan | 20 | |||
| 11/2/2019 | North Carolina Wesleyan | 48 | at | Methodist (4-6,3-4) | 24 | |||
| 11/9/2019 | North Carolina Wesleyan | 23 | at | Huntingdon AL (8-4,6-1) | 7 | |||
| 11/16/2019 | Maryville (3-7,3-4) | 0 | at | North Carolina Wesleyan | 23 |
| vs North Carolina Wesleyan | vs Other Opponents | North Carolina Wesleyan compared to OOs | |
| Record: | 4-6 | 50-43 | |
| Points Scored: | 25.40 | 27.65 | 2.25 |
| Points Allowed: | 30.50 | 26.19 | 4.31 |
| Margin: | -5.10 | 1.46 | 6.56 |
| Total Points: | 55.90 | 53.84 | 2.06 |