| 9/7/2019 | Henderson State | 35 | at | Oklahoma Baptist (7-4,7-4) | 28 | | | |
| 9/14/2019 | Southern Nazarene (2-9,2-9) | 6 | at | Henderson State | 34 | | | |
| 9/21/2019 | Arkansas Tech (3-8,3-8) | 21 | at | Henderson State | 27 | | | |
| 9/28/2019 | Henderson State | 13 | at | Harding (10-2,10-1) | 14 | | | |
| 10/5/2019 | Northwestern Oklahoma State (4-7,4-7) | 7 | at | Henderson State | 47 | | | |
| 10/12/2019 | Henderson State | 35 | at | Southwestern Oklahoma State (3-8,3-8) | 7 | | | |
| 10/19/2019 | East Central (3-8,3-8) | 17 | at | Henderson State | 48 | | | |
| 10/26/2019 | Henderson State | 41 | at | Southeastern Oklahoma State (1-10,1-10) | 27 | | | |
| 11/2/2019 | Henderson State | 27 | at | Arkansas-Monticello (5-6,5-6) | 20 | | | |
| 11/9/2019 | Southern Arkansas (8-4,8-3) | 31 | at | Henderson State | 38 | | | |
| 11/16/2019 | Henderson State | 21 | at | Ouachita (11-1,11-0) | 24 | | | |
| 12/7/2019 | Missouri Western (9-3) | 35 | at | Henderson State | 14 | | | MAIAA |