| 8/29/2019 | Ottawa AZ | 48 | at | Doane | 7 | | | @ GPAC |
| 8/31/2019 | Montana State-Northern | 20 | at | Arizona Christian | 14 | | | Front |
| Panhandle State | 22 | at | Hastings | 40 | | | @ GPAC |
| Texas Wesleyan | 24 | at | Kansas Wesleyan | 48 | | | @ KCAC |
| Missouri Baptist | 10 | at | Lyon | 14 | | | MSFA |
| Tabor | 40 | at | Southwestern Assemblies of God | 20 | | | KCAC |
| St Mary KS | 13 | at | Wayland Baptist | 35 | | | KCAC |
| 9/7/2019 | Arizona Christian | 14 | at | Abilene Christian | 66 | | | @ SLC (1AA) |
| Lyon | 20 | at | Hendrix | 28 | | | @ SAA (D3) |
| Texas Wesleyan | 13 | at | Houston Baptist | 58 | | | @ SLC (1AA) |
| Langston | 21 | vs | McPherson | 20 | | Wichita KS | vs KCAC |
| Western New Mexico | 31 | at | Ottawa AZ | 38 | | | LSC (D2) |
| Panhandle State | 0 | at | Sam Houston | 77 | | | @ SLC (1AA) |
| Wayland Baptist | 7 | at | Texas-Permian Basin | 60 | | | @ LSC (D2) |
| 9/14/2019 | Langston | 15 | at | Ark Pine Bluff | 53 | | | @ SWAC (1AA) |
| Austin | 27 | at | Southwestern Assemblies of God | 26 | | | SAA (D3) |
| Lane | 29 | at | Texas College | 0 | | | SIAC (D2) |
| 9/21/2019 | Panhandle State | 14 | at | Langston | 35 | | | |
| Texas Wesleyan | 38 | at | Ottawa AZ | 42 | | | |
| Lyon | 32 | at | Texas College | 17 | | | |
| Arizona Christian | 40 | at | Wayland Baptist | 27 | | | |
| 9/28/2019 | Southwestern Assemblies of God | 20 | at | Arizona Christian | 27 | | | |
| Texas Wesleyan | 45 | at | Lyon | 53 | | | |
| Wayland Baptist | 21 | at | Ottawa AZ | 80 | | | |
| Panhandle State | 34 | at | Texas College | 8 | | | |
| 10/5/2019 | Langston | 60 | at | Lyon | 7 | | | |
| Ottawa AZ | 47 | at | Panhandle State | 7 | | | |
| Southwestern Assemblies of God | 44 | at | Texas Wesleyan | 52 | 3OT | | |
| Texas College | 18 | at | Wayland Baptist | 40 | | | |
| 10/12/2019 | Arizona Christian | 16 | at | Langston | 34 | | | |
| Texas Wesleyan | 28 | at | Panhandle State | 34 | 2OT | | |
| Lyon | 38 | at | Southwestern Assemblies of God | 22 | | | |
| Ottawa AZ | 76 | at | Texas College | 21 | | | |
| 10/19/2019 | Panhandle State | 14 | at | Arizona Christian | 34 | | | |
| Langston | 7 | at | Ottawa AZ | 27 | | | |
| Wayland Baptist | 24 | at | Southwestern Assemblies of God | 14 | | | |
| Texas College | 24 | at | Texas Wesleyan | 61 | | | |
| 10/26/2019 | Ottawa AZ | 47 | at | Arizona Christian | 7 | | | |
| Texas Wesleyan | 7 | at | Langston | 69 | | | |
| Wayland Baptist | 7 | at | Lyon | 42 | | | |
| Southwestern Assemblies of God | 17 | at | Texas College | 24 | | | |
| 11/2/2019 | Lyon | 18 | at | Ottawa AZ | 14 | | | |
| Langston | 21 | at | Southwestern Assemblies of God | 14 | | | |
| Bethel KS | 51 | at | Texas College | 14 | | | KCAC |
| Arizona Christian | 45 | at | Texas Wesleyan | 35 | | | |
| Panhandle State | 14 | at | Wayland Baptist | 35 | | | |
| 11/9/2019 | Texas College | 7 | at | Langston | 44 | | | |
| Arizona Christian | 9 | at | Lyon | 7 | | | |
| Southwestern Assemblies of God | 0 | at | Panhandle State | 35 | | | |
| Wayland Baptist | 6 | at | Texas Wesleyan | 24 | | | |
| 11/16/2019 | Texas College | 20 | at | Arizona Christian | 24 | | | |
| Lyon | 27 | at | Panhandle State | 21 | | | |
| Ottawa AZ | 33 | at | Southwestern Assemblies of God | 14 | | | |
| Langston | 35 | at | Wayland Baptist | 20 | | | |
| 11/23/2019 | Ottawa AZ | 23 | at | College of Idaho | 70 | | NAIA Playoffs | @ Front |