| 8/31/2019 | Missouri Baptist | 10 | at | Lyon | 14 | @ Soon | ||
| St Francis IL | 0 | at | Morningside | 80 | @ GPAC | |||
| Trinity International | 28 | at | Presentation | 26 | @ NSAA | |||
| 9/7/2019 | Indiana Wesleyan | 27 | at | Butler | 30 | OT | @ Pio (1AA) | |
| Concordia MI | 17 | at | Kentucky Wesleyan | 14 | @ GMAC (D2) | |||
| St Xavier | 45 | at | Lawrence Tech | 13 | ||||
| Saint Ambrose | 45 | at | Missouri Baptist | 37 | ||||
| Taylor | 14 | at | Robert Morris IL | 31 | ||||
| Olivet Nazarene | 18 | at | Siena Heights | 20 | ||||
| St Francis IN | 56 | at | St Francis IL | 6 | ||||
| Trinity International | 3 | at | St Thomas | 69 | @ MIA (D3) | |||
| 9/14/2019 | Taylor | 17 | at | Butler | 14 | @ Pio (1AA) | ||
| Missouri Baptist | 22 | at | Indiana Wesleyan | 23 | ||||
| Wisconsin Lutheran | 14 | at | Lawrence Tech | 34 | NAC (D3) | |||
| Saint Ambrose | 14 | at | Marian IN | 49 | ||||
| Concordia MI | 22 | at | Olivet Nazarene | 14 | ||||
| Robert Morris IL | 0 | at | Siena Heights | 6 | ||||
| St Francis IL | 27 | at | Trinity International | 22 | ||||
| 9/21/2019 | St Francis IL | 7 | at | Concordia MI | 30 | |||
| Lawrence Tech | 31 | at | Olivet Nazarene | 49 | ||||
| St Francis IN | 29 | at | Robert Morris IL | 16 | ||||
| Siena Heights | 20 | at | Saint Ambrose | 10 | ||||
| Wisconsin-Whitewater | 28 | at | St Xavier | 20 | WIAC (D3) | |||
| Missouri Baptist | 7 | at | Taylor | 17 | ||||
| Marian IN | 55 | at | Trinity International | 0 | ||||
| 9/28/2019 | Olivet Nazarene | 24 | at | Indiana Wesleyan | 28 | |||
| St Francis IL | 55 | at | Lawrence Tech | 27 | ||||
| Robert Morris IL | 7 | at | Marian IN | 49 | ||||
| Missouri Baptist | 47 | at | Midland U. | 44 | @ GPAC | |||
| Trinity International | 2 | at | Siena Heights | 63 | ||||
| Saint Ambrose | 13 | at | St Francis IN | 31 | ||||
| Concordia MI | 42 | at | St Xavier | 35 | ||||
| 10/5/2019 | Siena Heights | 7 | at | Concordia MI | 10 | |||
| St Francis IN | 10 | at | Marian IN | 28 | ||||
| Olivet Nazarene | 28 | at | Missouri Baptist | 13 | ||||
| Robert Morris IL | 38 | at | St Francis IL | 27 | ||||
| Trinity International | 26 | at | St Xavier | 58 | ||||
| Indiana Wesleyan | 14 | at | Taylor | 13 | ||||
| 10/12/2019 | Lawrence Tech | 10 | at | Indiana Wesleyan | 45 | |||
| Saint Ambrose | 17 | at | Olivet Nazarene | 7 | ||||
| St Xavier | 31 | at | Robert Morris IL | 28 | ||||
| Taylor | 0 | at | Siena Heights | 42 | ||||
| Concordia MI | 27 | at | St Francis IN | 34 | ||||
| Missouri Baptist | 20 | at | Trinity International | 13 | ||||
| 10/19/2019 | Siena Heights | 41 | at | Lawrence Tech | 20 | |||
| Concordia MI | 13 | at | Marian IN | 28 | ||||
| St Xavier | 45 | at | Missouri Baptist | 34 | ||||
| Trinity International | 7 | at | Saint Ambrose | 63 | ||||
| Olivet Nazarene | 45 | at | St Francis IL | 28 | ||||
| Indiana Wesleyan | 30 | at | St Francis IN | 31 | ||||
| Lake Erie | 42 | at | Taylor | 20 | GMAC (D2) | |||
| 10/26/2019 | Taylor | 10 | at | Concordia MI | 34 | |||
| Lawrence Tech | 0 | at | Marian IN | 46 | ||||
| Robert Morris IL | 35 | at | Olivet Nazarene | 41 | ||||
| Siena Heights | 24 | at | St Francis IN | 14 | ||||
| St Francis IL | 28 | at | St Xavier | 44 | ||||
| Indiana Wesleyan | 66 | at | Trinity International | 0 | ||||
| 11/2/2019 | Siena Heights | 21 | at | Indiana Wesleyan | 28 | |||
| St Francis IN | 59 | at | Lawrence Tech | 20 | ||||
| Trinity International | 24 | at | Robert Morris IL | 52 | ||||
| St Xavier | 38 | at | Saint Ambrose | 17 | ||||
| Missouri Baptist | 34 | at | St Francis IL | 49 | ||||
| Marian IN | 41 | at | Taylor | 3 | ||||
| 11/9/2019 | Marian IN | 33 | at | Indiana Wesleyan | 21 | |||
| Concordia MI | 56 | at | Lawrence Tech | 7 | ||||
| Robert Morris IL | 25 | at | Missouri Baptist | 13 | ||||
| St Francis IL | 7 | at | Saint Ambrose | 17 | ||||
| Olivet Nazarene | 42 | at | St Xavier | 55 | ||||
| St Francis IN | 27 | at | Taylor | 14 | ||||
| 11/16/2019 | Indiana Wesleyan | 17 | at | Concordia MI | 28 | |||
| Walsh | 42 | at | Missouri Baptist | 7 | GMAC (D2) | |||
| Trinity International | 7 | at | Olivet Nazarene | 84 | ||||
| Saint Ambrose | 24 | at | Robert Morris IL | 28 | ||||
| Marian IN | 21 | at | Siena Heights | 7 | ||||
| St Xavier | 29 | at | St Francis IL | 27 | ||||
| Lawrence Tech | 26 | at | Taylor | 38 | ||||
| 11/23/2019 | Concordia MI | 30 | at | Grand View | 31 | NAIA Playoffs | @ HAAC | |
| Olivet Nazarene | 69 | at | Greenville | 8 | @ UMWAC (D3) | |||
| St Francis IN | 26 | at | Lindsey Wilson | 30 | NAIA Playoffs | @ MSC | ||
| Reinhardt | 7 | at | Marian IN | 17 | NAIA Playoffs | MSC | ||
| St Xavier | 25 | at | Northwestern IA | 20 | NAIA Playoffs | @ GPAC | ||
| 11/30/2019 | Cumberlands KY | 0 | at | Marian IN | 30 | NAIA Quarterfinals | MSC | |
| St Xavier | 0 | at | Morningside | 51 | NAIA Quarterfinals | @ GPAC | ||
| 12/7/2019 | Lindsey Wilson | 24 | at | Marian IN | 34 | NAIA Semifinal | MSC | |
| 12/21/2019 | Marian IN | 38 | vs | Morningside | 40 | NAIA Championship - Grambling LA | vs GPAC |