| 9/5/2019 | West Florida | 13 | at | Carson-Newman | 20 | @ SAC | ||
| Tusculum | 10 | at | Delta State | 24 | SAC | |||
| Newberry | 7 | at | North Greenville | 17 | SAC | |||
| 9/7/2019 | Valdosta State | 38 | at | Albany State GA | 3 | @ SIAC | ||
| Mississippi College | 7 | at | Alcorn State | 45 | @ SWAC (1AA) | |||
| West Georgia | 37 | at | Catawba | 9 | @ SAC | |||
| Shorter | 10 | at | East Tennessee St | 48 | @ SoCon (1AA) | |||
| Limestone | 18 | at | West Alabama | 35 | SAC | |||
| 9/8/2019 | Florida Tech | 23 | at | Savannah State | 22 | @ SIAC | ||
| 9/14/2019 | Delta State | 24 | at | Grand Valley State | 28 | @ GLIAC | ||
| West Georgia | 24 | at | Limestone | 14 | @ SAC | |||
| Albany State GA | 17 | at | Mississippi College | 24 | SIAC | |||
| Florida Tech | 30 | at | Newberry | 28 | @ SAC | |||
| West Florida | 42 | at | Shorter | 14 | ||||
| West Alabama | 47 | at | Tusculum | 14 | @ SAC | |||
| Ohio Dominican | 21 | at | Valdosta State | 48 | GMAC | |||
| North Greenville | 17 | at | Western Carolina | 20 | @ SoCon (1AA) | |||
| 9/21/2019 | Florida Tech | 28 | at | Delta State | 30 | |||
| Shorter | 23 | at | Fort Valley State | 30 | @ SIAC | |||
| North Greenville | 27 | at | Mississippi College | 39 | ||||
| West Alabama | 27 | at | Valdosta State | 44 | ||||
| Virginia U-Lynchburg | 0 | at | West Florida | 69 | None (Unk?) | |||
| Albany State GA | 26 | at | West Georgia | 14 | SIAC | |||
| 9/28/2019 | West Georgia | 10 | at | Florida Tech | 44 | |||
| Delta State | 34 | at | North Greenville | 9 | ||||
| Valdosta State | 44 | at | Shorter | 7 | ||||
| Tuskegee | 16 | at | West Alabama | 36 | SIAC | |||
| Mississippi College | 21 | at | West Florida | 27 | ||||
| 10/5/2019 | Fort Valley State | 33 | at | Florida Tech | 29 | SIAC | ||
| Mississippi College | 17 | at | Valdosta State | 42 | ||||
| North Greenville | 29 | at | West Alabama | 28 | ||||
| Delta State | 3 | at | West Florida | 48 | ||||
| Shorter | 34 | at | West Georgia | 44 | ||||
| 10/12/2019 | Valdosta State | 34 | at | Delta State | 13 | |||
| Florida Tech | 14 | at | Mississippi College | 34 | ||||
| West Georgia | 42 | at | North Greenville | 21 | ||||
| Shorter | 0 | at | West Alabama | 41 | ||||
| 10/19/2019 | West Alabama | 7 | at | Delta State | 14 | |||
| North Greenville | 7 | at | Shorter | 0 | ||||
| Florida Tech | 28 | at | Valdosta State | 55 | ||||
| West Florida | 30 | at | West Georgia | 2 | ||||
| 10/26/2019 | West Florida | 38 | at | Florida Tech | 14 | |||
| Shorter | 20 | at | Mississippi College | 41 | ||||
| Valdosta State | 20 | at | North Greenville | 15 | ||||
| West Georgia | 33 | at | West Alabama | 17 | ||||
| 11/2/2019 | West Alabama | 13 | at | Florida Tech | 10 | |||
| Delta State | 38 | at | Shorter | 6 | ||||
| North Greenville | 14 | at | West Florida | 17 | ||||
| Mississippi College | 21 | at | West Georgia | 35 | ||||
| 11/9/2019 | West Georgia | 20 | at | Delta State | 35 | |||
| Florida Tech | 17 | at | North Greenville | 14 | 2OT | |||
| Allen | 7 | at | Shorter | 37 | NAIAInd (NAIA) | |||
| West Florida | 21 | at | Valdosta State | 26 | ||||
| Mississippi College | 21 | at | West Alabama | 35 | ||||
| 11/16/2019 | Shorter | 3 | at | Florida Tech | 42 | |||
| Delta State | 13 | at | Mississippi College | 37 | ||||
| West Alabama | 37 | at | West Florida | 48 | ||||
| Valdosta State | 42 | at | West Georgia | 14 | ||||
| 11/23/2019 | West Florida | 38 | at | Wingate | 17 | D2 Playoff round 1 | @ SAC | |
| 11/30/2019 | West Florida | 38 | at | Valdosta State | 35 | D2 Playoff Round 2 | ||
| 12/7/2019 | West Florida | 43 | at | Lenoir-Rhyne | 38 | D2 Quarterfinals | @ SAC | |
| 12/14/2019 | West Florida | 28 | at | Ferris State | 14 | D2 Semifinal | @ GLIAC | |
| 12/21/2019 | West Florida | 48 | vs | Minnesota State-Mankato | 40 | D2 Championship - McKinney TX | vs NSIC |