| 9/5/2019 | Indianapolis | 24 | at | Ashland | 9 | @ GLIAC | ||
| Lincoln MO | 27 | at | Washburn | 49 | @ MAIAA | |||
| 9/7/2019 | Quincy | 38 | at | Central State | 8 | @ SIAC | ||
| Truman State | 10 | at | Drake | 7 | @ Pio (1AA) | |||
| Missouri S&T | 28 | at | Eastern New Mexico | 35 | @ LSC | |||
| McKendree | 9 | at | Northern Michigan | 30 | @ GLIAC | |||
| Southwest Baptist | 9 | at | William Jewell | 29 | ||||
| 9/12/2019 | Missouri Southern | 38 | at | Lincoln MO | 14 | MAIAA | ||
| 9/14/2019 | Hillsdale | 21 | at | Indianapolis | 48 | GMAC | ||
| Quincy | 34 | at | Kentucky Wesleyan | 16 | @ GMAC | |||
| Michigan Tech | 24 | at | McKendree | 19 | GLIAC | |||
| Azusa Pacific | 17 | at | Missouri S&T | 51 | GNWAC | |||
| Central State | 3 | at | Southwest Baptist | 38 | SIAC | |||
| Wayne State MI | 12 | at | Truman State | 35 | GLIAC | |||
| West Texas A&M | 49 | at | William Jewell | 21 | LSC | |||
| 9/21/2019 | Lincoln MO | 0 | at | Central Oklahoma | 63 | @ MAIAA | ||
| Southwest Baptist | 20 | at | Kentucky Wesleyan | 13 | @ GMAC | |||
| William Jewell | 16 | at | Lindenwood | 28 | @ MAIAA | |||
| Indianapolis | 63 | at | McKendree | 21 | ||||
| Miles | 21 | at | Missouri S&T | 49 | SIAC | |||
| Wayne State MI | 33 | at | Quincy | 7 | GLIAC | |||
| Valparaiso | 7 | at | Truman State | 38 | Pio (1AA) | |||
| 9/28/2019 | Southwest Baptist | 6 | at | Indianapolis | 49 | |||
| Emporia State | 50 | at | Lincoln MO | 7 | MAIAA | |||
| Chowan | 35 | at | McKendree | 42 | CIAA | |||
| Truman State | 63 | at | Quincy | 14 | ||||
| 9/29/2019 | Missouri S&T | 41 | at | William Jewell | 24 | |||
| 10/5/2019 | Lindenwood | 45 | at | McKendree | 37 | MAIAA | ||
| Quincy | 13 | at | Missouri S&T | 21 | ||||
| Lincoln MO | 14 | at | Pittsburg State | 56 | @ MAIAA | |||
| Southwest Baptist | 7 | at | Truman State | 52 | ||||
| Indianapolis | 59 | at | William Jewell | 7 | ||||
| 10/12/2019 | Quincy | 19 | at | Indianapolis | 59 | |||
| Nebraska-Kearney | 44 | at | Lincoln MO | 0 | MAIAA | |||
| Truman State | 24 | at | Lindenwood | 28 | @ MAIAA | |||
| William Jewell | 30 | at | Southwest Baptist | 32 | ||||
| Missouri S&T | 23 | at | Texas Southern | 20 | @ SWAC (1AA) | |||
| McKendree | 28 | at | Wheeling Jesuit | 14 | @ MtnE | |||
| 10/19/2019 | Northeastern State | 9 | at | Lincoln MO | 27 | MAIAA | ||
| Quincy | 48 | at | Southwest Baptist | 34 | ||||
| Missouri S&T | 39 | at | Truman State | 41 | ||||
| McKendree | 42 | at | William Jewell | 12 | ||||
| 10/26/2019 | Missouri S&T | 7 | at | Indianapolis | 48 | |||
| Southwest Baptist | 14 | at | McKendree | 24 | ||||
| Lincoln MO | 9 | at | Northwest Missouri State | 56 | @ MAIAA | |||
| Lindenwood | 33 | at | Quincy | 27 | MAIAA | |||
| Truman State | 49 | at | William Jewell | 27 | ||||
| 11/2/2019 | William Jewell | 10 | at | Grand Valley State | 63 | @ GLIAC | ||
| Fort Hays State | 66 | at | Lincoln MO | 6 | MAIAA | |||
| Indianapolis | 27 | at | Lindenwood | 34 | @ MAIAA | |||
| Southwest Baptist | 0 | at | Missouri S&T | 62 | ||||
| Apprentice | 3 | at | Quincy | 49 | None (Unk?) | |||
| McKendree | 17 | at | Truman State | 45 | ||||
| 11/9/2019 | Lincoln MO | 6 | at | Central Missouri | 73 | @ MAIAA | ||
| Southwest Baptist | 17 | at | Central Washington | 72 | @ GNWAC | |||
| Truman State | 28 | at | Indianapolis | 44 | ||||
| Missouri S&T | 31 | at | Lindenwood | 37 | OT | @ MAIAA | ||
| Quincy | 34 | at | McKendree | 62 | ||||
| Tarleton State | 58 | at | William Jewell | 3 | LSC | |||
| 11/16/2019 | Lake Erie | 6 | at | Indianapolis | 70 | GMAC | ||
| Missouri Western | 71 | at | Lincoln MO | 8 | MAIAA | |||
| McKendree | 50 | at | Missouri S&T | 51 | ||||
| William Jewell | 42 | at | Quincy | 47 | ||||
| Lindenwood | 42 | at | Southwest Baptist | 10 | MAIAA | |||
| Truman State | 24 | at | Urbana | 14 | @ MtnE | |||
| 11/23/2019 | Indianapolis | 27 | at | Central Missouri | 37 | D2 Playoff round 1 | @ MAIAA | |
| 12/7/2019 | Ohio Dominican | 7 | vs | Truman State | 21 | Hobart IN | vs GMAC |