| 8/25/2018 | Peru State | 21 | at | Hastings (5-6) | 25 | | | at GPAC |
| 9/8/2018 | Peru State | 21 | at | Central Methodist (4-6,4-6) | 42 | | | |
| 9/15/2018 | Evangel (9-2,8-2) | 35 | at | Peru State | 13 | | | |
| 9/22/2018 | Missouri Valley (3-7,3-7) | 14 | at | Peru State | 24 | | | |
| 9/29/2018 | Peru State | 24 | at | MidAmerica Nazarene (4-7,4-6) | 19 | | | |
| 10/6/2018 | Baker (9-3,8-2) | 35 | at | Peru State | 0 | | | |
| 10/13/2018 | Grand View (8-3,8-2) | 45 | at | Peru State | 28 | | | |
| 10/20/2018 | Peru State | 26 | at | William Penn (4-7,4-6) | 20 | 2OT | | |
| 10/27/2018 | Peru State | 33 | at | Graceland (1-10,1-9) | 36 | | | |
| 11/3/2018 | Culver-Stockton (4-7,3-7) | 38 | at | Peru State | 35 | | | |
| 11/10/2018 | Peru State | 23 | at | Benedictine KS (13-2,9-1) | 41 | | | |