| 8/25/2018 | Culver-Stockton | 56 | at | Trinity Bible (0-4) | 0 | | | at None |
| 9/1/2018 | Central Methodist (4-6,4-6) | 22 | at | Culver-Stockton | 35 | | | |
| 9/8/2018 | MidAmerica Nazarene (4-7,4-6) | 46 | at | Culver-Stockton | 20 | | | |
| 9/15/2018 | Culver-Stockton | 10 | at | Baker (9-3,8-2) | 51 | | | |
| 9/22/2018 | Culver-Stockton | 17 | at | Evangel (9-2,8-2) | 20 | | | |
| 10/6/2018 | Culver-Stockton | 16 | at | Missouri Valley (3-7,3-7) | 26 | | | |
| 10/13/2018 | Culver-Stockton | 21 | at | William Penn (4-7,4-6) | 24 | | | |
| 10/20/2018 | Benedictine KS (13-2,9-1) | 49 | at | Culver-Stockton | 13 | | | |
| 10/27/2018 | Grand View (8-3,8-2) | 29 | at | Culver-Stockton | 27 | | | |
| 11/3/2018 | Culver-Stockton | 38 | at | Peru State (3-8,3-7) | 35 | | | |
| 11/10/2018 | Culver-Stockton | 42 | at | Graceland (1-10,1-9) | 38 | | | |