| 9/1/2018 | Wilmington | 49 | at | Earlham (0-10) | 7 | at HCA | ||
| 9/15/2018 | Wilmington | 16 | at | Ohio Northern (5-5,4-5) | 49 | |||
| 9/22/2018 | Muskingum (4-6,3-6) | 31 | at | Wilmington | 24 | |||
| 9/29/2018 | Heidelberg (5-5,4-5) | 44 | at | Wilmington | 13 | |||
| 10/6/2018 | Wilmington | 7 | at | Mount Union (14-1,9-0) | 63 | |||
| 10/13/2018 | Wilmington | 21 | at | Marietta (7-3,6-3) | 63 | |||
| 10/20/2018 | Baldwin-Wallace (8-2,7-2) | 35 | at | Wilmington | 33 | |||
| 10/27/2018 | John Carroll (9-2,8-1) | 66 | at | Wilmington | 19 | |||
| 11/3/2018 | Wilmington | 17 | at | Capital (3-7,3-6) | 38 | |||
| 11/10/2018 | Otterbein (2-8,1-8) | 34 | at | Wilmington | 24 |
| vs Wilmington | vs Other Opponents | Wilmington compared to OOs | |
| Record: | 9-1 | 48-48 | |
| Points Scored: | 43.00 | 28.54 | -14.46 |
| Points Allowed: | 22.30 | 30.88 | -8.58 |
| Margin: | 20.70 | -2.34 | -23.04 |
| Total Points: | 65.30 | 59.42 | 5.88 |