| 9/1/2018 | Muskingum (4-6) | 31 | at | Waynesburg | 24 | OAC | ||
| 9/8/2018 | Westminster PA (7-4,7-2) | 27 | at | Waynesburg | 12 | |||
| 9/15/2018 | Waynesburg | 13 | at | Bethany WV (5-5,5-4) | 22 | |||
| 9/22/2018 | Geneva (2-8,2-7) | 7 | at | Waynesburg | 10 | |||
| 9/29/2018 | Waynesburg | 24 | at | Thiel (0-10,0-9) | 21 | |||
| 10/6/2018 | Carnegie Mellon (6-4,5-4) | 21 | at | Waynesburg | 24 | |||
| 10/13/2018 | Waynesburg | 3 | at | Grove City (8-3,6-3) | 28 | |||
| 10/20/2018 | Waynesburg | 12 | at | St Vincent (1-9,1-8) | 10 | |||
| 11/3/2018 | Waynesburg | 17 | at | Case Western Reserve (8-2,7-2) | 41 | |||
| 11/10/2018 | Washington & Jefferson (9-2,8-1) | 33 | at | Waynesburg | 14 |
| vs Waynesburg | vs Other Opponents | Waynesburg compared to OOs | |
| Record: | 6-4 | 44-49 | |
| Points Scored: | 24.10 | 25.26 | 1.16 |
| Points Allowed: | 15.30 | 27.19 | -11.89 |
| Margin: | 8.80 | -1.93 | -10.73 |
| Total Points: | 39.40 | 52.45 | -13.05 |