| 9/1/2018 | Capital (3-7) | 21 | at | Mt St Joseph | 59 | OAC | ||
| 9/8/2018 | Mt St Joseph | 19 | at | Morehead State (3-8) | 48 | at Pio | ||
| 9/15/2018 | Rose-Hulman (5-5,5-3) | 35 | at | Mt St Joseph | 54 | |||
| 9/22/2018 | Mt St Joseph | 59 | at | Earlham (0-10,0-8) | 2 | |||
| 9/29/2018 | Mt St Joseph | 21 | at | Bluffton (3-7,3-5) | 7 | |||
| 10/6/2018 | Manchester (4-6,4-4) | 27 | at | Mt St Joseph | 49 | |||
| 10/13/2018 | Franklin (8-2,7-1) | 42 | at | Mt St Joseph | 34 | |||
| 10/20/2018 | Mt St Joseph | 20 | at | Defiance (1-9,1-7) | 0 | |||
| 10/27/2018 | Mt St Joseph | 19 | at | Hanover (7-4,7-1) | 15 | |||
| 11/3/2018 | Anderson (2-8,2-6) | 6 | at | Mt St Joseph | 45 |
| vs Mt St Joseph | vs Other Opponents | Mt St Joseph compared to OOs | |
| Record: | 2-8 | 34-58 | |
| Points Scored: | 20.30 | 25.22 | 4.92 |
| Points Allowed: | 37.90 | 33.95 | 3.95 |
| Margin: | -17.60 | -8.73 | 8.87 |
| Total Points: | 58.20 | 59.17 | -0.97 |