| 9/1/2018 | Kentucky State (0-10) | 31 | at | Slippery Rock | 38 | SIAC | ||
| 9/8/2018 | Slippery Rock | 21 | at | Shippensburg (6-5,6-4) | 25 | |||
| 9/15/2018 | Slippery Rock | 57 | at | Millersville (2-9,2-7) | 10 | |||
| 9/22/2018 | Seton Hill (1-10,1-8) | 26 | at | Slippery Rock | 49 | |||
| 9/29/2018 | Mercyhurst (5-6,5-4) | 21 | at | Slippery Rock | 41 | |||
| 10/6/2018 | Slippery Rock | 30 | at | Indiana PA (8-3,7-3) | 27 | |||
| 10/13/2018 | Edinboro (6-5,5-5) | 28 | at | Slippery Rock | 59 | |||
| 10/20/2018 | Slippery Rock | 28 | at | Clarion (4-7,3-7) | 13 | |||
| 10/27/2018 | Slippery Rock | 44 | at | California PA (7-4,7-3) | 21 | |||
| 11/3/2018 | Gannon (2-9,2-8) | 7 | at | Slippery Rock | 48 | |||
| 11/10/2018 | West Chester (10-1,9-0) | 33 | at | Slippery Rock | 10 | |||
| 11/17/2018 | Slippery Rock | 20 | at | LIU Post (10-1) | 14 | D2 Playoff Round 1 | at NE10 | |
| 11/24/2018 | Slippery Rock | 59 | at | New Haven (9-3) | 20 | at NE10 | ||
| 12/1/2018 | Slippery Rock | 17 | at | Notre Dame OH (13-1) | 21 | D2 Playoff | at MtnE |
| vs Slippery Rock | vs Other Opponents | Slippery Rock compared to OOs | |
| Record: | 3-11 | 80-63 | |
| Points Scored: | 21.21 | 28.07 | 6.86 |
| Points Allowed: | 37.21 | 23.98 | 13.23 |
| Margin: | -16.00 | 4.09 | 20.09 |
| Total Points: | 58.42 | 52.05 | 6.37 |