| 9/1/2018 | Seton Hill | 28 | at | Virginia Union (8-2) | 34 | at CIAA | ||
| 9/8/2018 | Seton Hill | 34 | at | East Stroudsburg (2-9,2-7) | 41 | |||
| 9/15/2018 | West Chester (10-1,9-0) | 59 | at | Seton Hill | 14 | |||
| 9/22/2018 | Seton Hill | 26 | at | Slippery Rock (11-3,8-2) | 49 | |||
| 9/29/2018 | Clarion (4-7,3-7) | 19 | at | Seton Hill | 16 | |||
| 10/6/2018 | Seton Hill | 28 | at | Gannon (2-9,2-8) | 48 | |||
| 10/13/2018 | Mercyhurst (5-6,5-4) | 33 | at | Seton Hill | 34 | |||
| 10/20/2018 | Seton Hill | 12 | at | Edinboro (6-5,5-5) | 56 | |||
| 10/27/2018 | Seton Hill | 14 | at | Indiana PA (8-3,7-3) | 56 | |||
| 11/3/2018 | California PA (7-4,7-3) | 49 | at | Seton Hill | 34 | |||
| 11/10/2018 | Notre Dame OH (13-1) | 41 | at | Seton Hill | 7 | MtnE |
| vs Seton Hill | vs Other Opponents | Seton Hill compared to OOs | |
| Record: | 10-1 | 66-49 | |
| Points Scored: | 44.09 | 29.83 | -14.26 |
| Points Allowed: | 22.45 | 23.48 | -1.03 |
| Margin: | 21.64 | 6.35 | -15.29 |
| Total Points: | 66.54 | 53.31 | 13.23 |