| 8/30/2018 | Ouachita | 29 | at | Northwestern Oklahoma State (4-7,4-7) | 21 | | | |
| 9/8/2018 | Southwestern Oklahoma State (3-8,3-8) | 8 | at | Ouachita | 41 | | | |
| 9/15/2018 | Ouachita | 32 | at | Southeastern Oklahoma State (6-5,6-5) | 16 | | | |
| 9/22/2018 | East Central (3-8,3-8) | 0 | at | Ouachita | 42 | | | |
| 9/29/2018 | Arkansas Tech (3-8,3-8) | 7 | at | Ouachita | 24 | | | |
| 10/6/2018 | Ouachita | 7 | at | Harding (9-3,9-2) | 3 | | | |
| 10/13/2018 | Ouachita | 58 | at | Oklahoma Baptist (5-6,5-6) | 21 | | | |
| 10/18/2018 | Southern Nazarene (3-8,3-8) | 0 | at | Ouachita | 41 | | | |
| 10/27/2018 | Ouachita | 35 | at | Arkansas-Monticello (6-6,6-5) | 10 | | | |
| 11/3/2018 | Southern Arkansas (8-4,8-3) | 10 | at | Ouachita | 35 | | | |
| 11/10/2018 | Ouachita | 38 | at | Henderson State (5-6,5-6) | 10 | | | |
| 11/24/2018 | Indianapolis (10-2) | 7 | at | Ouachita | 35 | | | GLV |
| 12/1/2018 | Ferris State (15-1) | 37 | at | Ouachita | 14 | | D2 Playoff | GLIAC |