| 9/1/2018 | Holy Cross (5-6,4-2) | 17 | at | Colgate | 24 | |||
| 9/8/2018 | Colgate | 10 | at | New Hampshire (4-7) | 3 | at CAAF | ||
| 9/15/2018 | Colgate | vs | Furman (6-4) | CCD | vs SoCon | |||
| 9/22/2018 | Lafayette (3-8,2-4) | 0 | at | Colgate | 45 | |||
| 9/29/2018 | Colgate | 23 | at | William & Mary (4-6) | 0 | at CAAF | ||
| 10/6/2018 | Colgate | 27 | at | Bucknell (1-10,1-5) | 3 | |||
| 10/13/2018 | Cornell (3-7) | 0 | at | Colgate | 31 | Ivy | ||
| 10/27/2018 | Georgetown (5-6,4-2) | 0 | at | Colgate | 38 | |||
| 11/3/2018 | Colgate | 41 | at | Fordham (2-9,2-4) | 0 | |||
| 11/10/2018 | Colgate | 48 | at | Lehigh (3-8,2-4) | 6 | |||
| 11/17/2018 | Colgate | 14 | at | Army (11-2) | 28 | at Ind | ||
| 12/1/2018 | James Madison (9-4) | 20 | at | Colgate | 23 | 1AA Playoff Round 2 | CAAF | |
| 12/8/2018 | Colgate | 0 | at | North Dakota State (15-0) | 35 | 1AA Playoff Quarterfinal | at MVC |
| vs Colgate | vs Other Opponents | Colgate compared to OOs | |
| Record: | 2-10 | 69-67 | |
| Points Scored: | 9.33 | 23.96 | 14.63 |
| Points Allowed: | 27.00 | 23.71 | 3.29 |
| Margin: | -17.67 | 0.25 | 17.92 |
| Total Points: | 36.33 | 47.67 | -11.34 |