| 9/1/2018 | William & Mary | 14 | at | Bucknell | 7 | CAAF | ||
| Holy Cross | 17 | at | Colgate | 24 | ||||
| St Francis PA | 19 | at | Lehigh | 21 | NE | |||
| Georgetown | 39 | at | Marist | 14 | @ Pio | |||
| Lafayette | 6 | at | Sacred Heart | 35 | @ NE | |||
| Fordham | 10 | at | UNC-Charlotte | 34 | @ CUSA (1A) | |||
| 9/8/2018 | Holy Cross | 14 | at | Boston College | 62 | @ ACC (1A) | ||
| Sacred Heart | 30 | at | Bucknell | 14 | NE | |||
| Lafayette | 0 | at | Delaware | 37 | @ CAAF | |||
| Campbell | 13 | at | Georgetown | 8 | BigS | |||
| Villanova | 31 | at | Lehigh | 9 | CAAF | |||
| Colgate | 10 | at | New Hampshire | 3 | @ CAAF | |||
| Fordham | 7 | at | Richmond | 52 | @ CAAF | |||
| 9/15/2018 | Georgetown | 0 | at | Dartmouth | 41 | @ Ivy | ||
| Stony Brook | 28 | at | Fordham | 6 | CAAF | |||
| Colgate | vs | Furman | CCD | vs SoCon | ||||
| Yale | 28 | at | Holy Cross | 31 | OT | Ivy | ||
| Monmouth NJ | 24 | at | Lafayette | 20 | BigS | |||
| Lehigh | 21 | at | Navy | 51 | @ AAC (1A) | |||
| Bucknell | 17 | at | Pennsylvania | 34 | @ Ivy | |||
| 9/22/2018 | Lafayette | 0 | at | Colgate | 45 | |||
| Central Conn | 24 | at | Fordham | 13 | NE | |||
| Columbia | 23 | at | Georgetown | 15 | Ivy | |||
| Dartmouth | 34 | at | Holy Cross | 14 | Ivy | |||
| Lehigh | 10 | at | Pennsylvania | 30 | @ Ivy | |||
| Bucknell | 7 | at | Villanova | 49 | @ CAAF | |||
| 9/29/2018 | Georgetown | 7 | at | Brown | 35 | @ Ivy | ||
| Bucknell | 19 | at | Holy Cross | 16 | ||||
| Central Conn | 24 | at | Lafayette | 31 | NE | |||
| Colgate | 23 | at | William & Mary | 0 | @ CAAF | |||
| 10/6/2018 | Colgate | 27 | at | Bucknell | 3 | |||
| Georgetown | 23 | at | Fordham | 11 | ||||
| Holy Cross | 0 | at | New Hampshire | 28 | @ CAAF | |||
| Lehigh | 7 | at | Princeton | 66 | @ Ivy | |||
| 10/12/2018 | Holy Cross | 31 | at | Harvard | 33 | @ Ivy | ||
| 10/13/2018 | Cornell | 0 | at | Colgate | 31 | Ivy | ||
| Georgetown | 13 | at | Lafayette | 6 | ||||
| Fordham | 43 | at | Lehigh | 14 | ||||
| Bucknell | 19 | at | Monmouth NJ | 36 | @ BigS | |||
| 10/20/2018 | Lafayette | 29 | at | Bucknell | 27 | |||
| Bryant | 42 | at | Fordham | 41 | NE | |||
| Lehigh | 16 | at | Georgetown | 22 | 2OT | |||
| 10/27/2018 | Georgetown | 0 | at | Colgate | 38 | |||
| Lafayette | 21 | at | Fordham | 13 | ||||
| Lehigh | 0 | at | Holy Cross | 56 | ||||
| 11/3/2018 | Colgate | 41 | at | Fordham | 0 | |||
| Holy Cross | 40 | at | Lafayette | 14 | ||||
| Bucknell | 17 | at | Lehigh | 45 | ||||
| 11/10/2018 | Lafayette | 13 | at | Army | 31 | @ Ind (1A) | ||
| Bucknell | 3 | at | Georgetown | 14 | ||||
| Fordham | 13 | at | Holy Cross | 17 | ||||
| Colgate | 48 | at | Lehigh | 6 | ||||
| 11/17/2018 | Colgate | 14 | at | Army | 28 | @ Ind (1A) | ||
| Fordham | 17 | at | Bucknell | 14 | ||||
| Holy Cross | 32 | at | Georgetown | 31 | ||||
| Lehigh | 34 | at | Lafayette | 3 | ||||
| 12/1/2018 | James Madison | 20 | at | Colgate | 23 | 1AA Playoff Round 2 | CAAF | |
| 12/8/2018 | Colgate | 0 | at | North Dakota State | 35 | 1AA Playoff Quarterfinal | @ MVC |