| 9/15/2018 | Bucknell (1-10) | 17 | at | Pennsylvania | 34 | Pat | ||
| 9/22/2018 | Lehigh (3-8) | 10 | at | Pennsylvania | 30 | Pat | ||
| 9/29/2018 | Pennsylvania | 14 | at | Dartmouth (9-1,6-1) | 37 | |||
| 10/6/2018 | Pennsylvania | 31 | at | Sacred Heart (7-4) | 27 | at NE | ||
| 10/13/2018 | Columbia (6-4,3-4) | 10 | at | Pennsylvania | 13 | |||
| 10/19/2018 | Yale (5-5,3-4) | 23 | at | Pennsylvania | 10 | |||
| 10/27/2018 | Pennsylvania | 13 | at | Brown (1-9,0-7) | 7 | |||
| 11/2/2018 | Pennsylvania | 20 | at | Cornell (3-7,2-5) | 7 | |||
| 11/10/2018 | Harvard (6-4,4-3) | 29 | at | Pennsylvania | 7 | |||
| 11/17/2018 | Pennsylvania | 14 | at | Princeton (10-0,7-0) | 42 |
| vs Pennsylvania | vs Other Opponents | Pennsylvania compared to OOs | |
| Record: | 4-6 | 47-46 | |
| Points Scored: | 20.90 | 25.85 | 4.95 |
| Points Allowed: | 18.60 | 26.00 | -7.40 |
| Margin: | 2.30 | -0.15 | -2.45 |
| Total Points: | 39.50 | 51.85 | -12.35 |