| 9/2/2017 | Tarleton State (6-6) | 16 | at | Delta State | 34 | LSC | ||
| 9/9/2017 | Chowan (4-6) | 13 | at | Delta State | 42 | CIAA | ||
| 9/16/2017 | West Georgia (9-4,5-4) | 7 | at | Delta State | 17 | |||
| 9/23/2017 | Delta State | 54 | at | Shorter (0-11,0-8) | 20 | |||
| 9/30/2017 | Delta State | 30 | at | Mississippi College (1-9,1-7) | 17 | |||
| 10/7/2017 | West Alabama (10-3,8-2) | 29 | at | Delta State | 26 | |||
| 10/14/2017 | Delta State | 28 | at | West Florida (11-4,7-3) | 25 | |||
| 10/21/2017 | Valdosta State (5-4,5-3) | 34 | at | Delta State | 13 | |||
| 10/28/2017 | Delta State | 7 | at | North Alabama (5-5,5-3) | 20 | |||
| 11/4/2017 | Delta State | 33 | at | North Greenville (4-6) | 30 | at D2Ind | ||
| 11/11/2017 | Florida Tech (5-6,3-5) | 20 | at | Delta State | 42 | |||
| 11/18/2017 | Delta State | 45 | at | Bowie State (9-2) | 35 | at CIAA | ||
| 11/25/2017 | Delta State | 20 | at | West Alabama (10-3,8-2) | 27 | D2 Playoff Round 2 |
| vs Delta State | vs Other Opponents | Delta State compared to OOs | |
| Record: | 4-9 | 73-60 | |
| Points Scored: | 22.54 | 30.06 | 7.52 |
| Points Allowed: | 30.08 | 24.83 | 5.25 |
| Margin: | -7.54 | 5.23 | 12.77 |
| Total Points: | 52.62 | 54.89 | -2.27 |