D2
8 Jan 2018 22:16:00
8/31/2017 | Ohio Dominican | 34 | at | California PA | 36 | | | GMAC |
| East Stroudsburg | 20 | at | Fairmont State | 16 | | | @ MtnE |
| Ashland | 23 | at | Indiana PA | 26 | | | GLIAC |
| Clarion | 0 | at | Tennessee-Martin | 36 | | | @ OVC (1AA) |
| Bentley | 9 | at | West Chester | 51 | | | NE10 |
9/2/2017 | Stonehill | 44 | at | Bloomsburg | 28 | | | NE10 |
| Lincoln PA | 28 | at | Cheyney | 56 | | | CIAA |
| Lake Erie | 3 | at | Edinboro | 30 | | | GMAC |
| Slippery Rock | 42 | at | Kentucky State | 21 | | | @ SIAC |
| Assumption | 31 | at | Kutztown | 28 | | | NE10 |
| Hillsdale | 19 | at | Mercyhurst | 11 | | | GMAC |
| Millersville | 20 | at | Pace | 28 | | | @ NE10 |
| Bowie State | 48 | at | Seton Hill | 7 | | | CIAA |
| American Int'l | 7 | at | Shippensburg | 41 | | | NE10 |
| Gannon | 55 | at | Southern Connecticut | 22 | | | @ NE10 |
| Lock Haven | 3 | at | St Francis PA | 69 | | | @ NE (1AA) |
9/9/2017 | Cheyney | 14 | at | California PA | 54 | | | |
| Bloomsburg | 29 | at | Clarion | 20 | | | |
| Lock Haven | 3 | at | Edinboro | 20 | | | |
| Shippensburg | 41 | at | Gannon | 33 | | | |
| East Stroudsburg | 14 | at | Indiana PA | 38 | | | |
| Kutztown | 21 | at | Mercyhurst | 16 | | | |
| Millersville | 45 | at | Seton Hill | 38 | | | |
| West Chester | 42 | at | Slippery Rock | 49 | | | |
9/16/2017 | Gannon | 10 | at | Bloomsburg | 27 | | | |
| Shippensburg | 31 | at | Clarion | 0 | | | |
| Mercyhurst | 25 | at | East Stroudsburg | 20 | | | |
| Cheyney | 16 | at | Indiana PA | 65 | | | |
| Seton Hill | 17 | at | Kutztown | 62 | | | |
| California PA | 29 | at | Millersville | 13 | | | |
| Lock Haven | 7 | at | Slippery Rock | 33 | | | |
| Edinboro | 28 | at | West Chester | 62 | | | |
9/23/2017 | Cheyney | 19 | at | Bloomsburg | 48 | | | |
| Seton Hill | 41 | at | California PA | 44 | | | |
| Mercyhurst | 21 | at | Clarion | 18 | | | |
| Shippensburg | 40 | at | East Stroudsburg | 0 | | | |
| Slippery Rock | 49 | at | Gannon | 45 | | | |
| Edinboro | 7 | at | Indiana PA | 38 | | | |
| Millersville | 21 | at | Kutztown | 41 | | | |
| West Chester | 35 | at | Lock Haven | 14 | | | |
9/30/2017 | East Stroudsburg | 33 | at | Cheyney | 13 | | | |
| Clarion | 10 | at | Edinboro | 45 | | | |
| Gannon | 22 | at | Mercyhurst | 24 | | | |
| Bloomsburg | 28 | at | Millersville | 21 | | | |
| Indiana PA | 57 | at | Seton Hill | 14 | | | |
| Lock Haven | 6 | at | Shippensburg | 37 | | | |
| California PA | 44 | at | Slippery Rock | 47 | OT | | |
| Kutztown | 21 | at | West Chester | 27 | | | |
10/5/2017 | Millersville | 12 | at | East Stroudsburg | 0 | | | |
10/7/2017 | Kutztown | 23 | at | Bloomsburg | 7 | | | |
| Seton Hill | 28 | at | Clarion | 33 | | | |
| Edinboro | 25 | at | Gannon | 47 | | | |
| California PA | 10 | at | Indiana PA | 26 | | | |
| Cheyney | 0 | at | Lock Haven | 62 | | | |
| Slippery Rock | 31 | at | Mercyhurst | 28 | | | |
| West Chester | 37 | at | Shippensburg | 27 | | | |
10/14/2017 | Clarion | 19 | at | California PA | 21 | | | |
| Shippensburg | 56 | at | Cheyney | 0 | | | |
| Mercyhurst | 25 | at | Edinboro | 28 | | | |
| East Stroudsburg | 9 | at | Kutztown | 41 | | | |
| Lock Haven | 21 | at | Millersville | 34 | | | |
| Gannon | 76 | at | Seton Hill | 31 | | | |
| Indiana PA | 34 | at | Slippery Rock | 17 | | | |
| Bloomsburg | 20 | at | West Chester | 19 | | | |
10/21/2017 | West Chester | 55 | at | Cheyney | 6 | | | |
| Indiana PA | 23 | at | Clarion | 17 | | | |
| Bloomsburg | 38 | at | East Stroudsburg | 28 | | | |
| Slippery Rock | 39 | at | Edinboro | 49 | | | |
| California PA | 38 | at | Gannon | 35 | | | |
| Kutztown | 55 | at | Lock Haven | 26 | | | |
| Seton Hill | 16 | at | Mercyhurst | 35 | | | |
| Millersville | 14 | at | Shippensburg | 51 | | | |
10/28/2017 | Lock Haven | 27 | at | Bloomsburg | 24 | | | |
| Mercyhurst | 21 | at | California PA | 31 | | | |
| Gannon | 26 | at | Indiana PA | 42 | | | |
| Shippensburg | 27 | at | Kutztown | 13 | | | |
| Cheyney | 7 | at | Millersville | 59 | | | |
| Edinboro | 69 | at | Seton Hill | 20 | | | |
| Clarion | 9 | at | Slippery Rock | 24 | | | |
| East Stroudsburg | 26 | at | West Chester | 31 | | | |
11/4/2017 | Kutztown | 65 | at | Cheyney | 0 | | | |
| California PA | 30 | at | Edinboro | 13 | | | |
| Clarion | 28 | at | Gannon | 38 | | | |
| East Stroudsburg | 37 | at | Lock Haven | 27 | | | |
| Indiana PA | 36 | at | Mercyhurst | 10 | | | |
| West Chester | 27 | at | Millersville | 24 | | | |
| Slippery Rock | 77 | at | Seton Hill | 38 | | | |
| Bloomsburg | 6 | at | Shippensburg | 20 | | | |
11/11/2017 | Clarion | 15 | at | Bloomsburg | 31 | | | |
| Edinboro | 63 | at | Cheyney | 0 | | | |
| California PA | 31 | at | East Stroudsburg | 14 | | | |
| Slippery Rock | 34 | at | Kutztown | 42 | | | |
| Mercyhurst | 23 | at | Lock Haven | 10 | | | |
| Gannon | 39 | at | Millersville | 7 | | | |
| Seton Hill | 13 | at | Shippensburg | 51 | | | |
| Indiana PA | 24 | at | West Chester | 7 | | | |
11/18/2017 | California PA | 31 | at | Assumption | 40 | | | @ NE10 |
| West Chester | 27 | at | Shippensburg | 6 | | | |
11/25/2017 | West Chester | 10 | at | Indiana PA | 44 | | D2 Playoff Round 2 | |
12/2/2017 | Assumption | 22 | at | Indiana PA | 27 | | D2 Playoff Quarterfinal | NE10 |
12/9/2017 | West Florida | 27 | at | Indiana PA | 17 | | D2 Playoff Semifinal | GSC |