| 8/31/2017 | Tusculum | 33 | at | North Greenville | 34 | SAC | ||
| Winston-Salem State | 34 | at | UNC Pembroke | 31 | CIAA | |||
| 9/9/2017 | UNC Pembroke | 66 | at | Elizabeth City State | 14 | @ CIAA | ||
| North Greenville | 10 | at | Lenoir-Rhyne | 22 | @ SAC | |||
| 9/16/2017 | North Greenville | 35 | at | Albany State GA | 27 | @ SIAC | ||
| Catawba | 41 | at | UNC Pembroke | 9 | SAC | |||
| 9/23/2017 | Limestone | 20 | at | North Greenville | 27 | SAC | ||
| Tusculum | 31 | at | UNC Pembroke | 10 | SAC | |||
| 9/30/2017 | North Greenville | 34 | at | Kennesaw St | 38 | @ BigS (1AA) | ||
| UNC Pembroke | 6 | at | Newberry | 28 | @ SAC | |||
| 10/7/2017 | North Greenville | 20 | at | Catawba | 26 | OT | @ SAC | |
| UNC Pembroke | 28 | at | Wingate | 31 | @ SAC | |||
| 10/14/2017 | Florida Tech | 42 | at | North Greenville | 31 | GSC | ||
| 10/21/2017 | North Greenville | 31 | at | Carson-Newman | 21 | @ SAC | ||
| UNC Pembroke | 22 | at | Concord | 31 | @ MtnE | |||
| 10/28/2017 | Lenoir-Rhyne | 10 | at | UNC Pembroke | 14 | SAC | ||
| 11/4/2017 | UNC Pembroke | 44 | at | Mars Hill | 56 | @ SAC | ||
| Delta State | 33 | at | North Greenville | 30 | GSC | |||
| 11/11/2017 | UNC Pembroke | 10 | at | Carson-Newman | 45 | @ SAC | ||
| North Greenville | 26 | at | West Alabama | 29 | @ GSC |