| 8/26/2017 | Missouri Baptist | 7 | at | Lyon | 28 | | | MSFA |
| Bacone | 7 | at | Robert Morris IL | 22 | | | @ MSFA |
| 8/31/2017 | McMurry | 0 | at | Panhandle State | 10 | | | ASWC (D3) |
| 9/2/2017 | Simon Fraser | 28 | at | Arizona Christian | 34 | | | GNWAC (D2) |
| Austin | 31 | at | Bacone | 18 | | | SAA (D3) |
| Lyon | 28 | at | Hendrix | 56 | | | @ SAA (D3) |
| Lincoln MO | 14 | at | Langston | 30 | | | GLV (D2) |
| Wayland Baptist | 20 | at | Louisiana College | 59 | | | @ ASWC (D3) |
| Texas Wesleyan | 14 | at | McPherson | 43 | | | @ KCAC |
| Howard Payne | 34 | at | Southwestern Assemblies of God | 63 | | | ASWC (D3) |
| Lane | 40 | at | Texas College | 20 | | | SIAC (D2) |
| 9/9/2017 | Wayland Baptist | 12 | at | Austin | 34 | | | @ SAA (D3) |
| Arizona Christian | 35 | at | Bacone | 7 | | | |
| Texas College | 0 | at | Hardin-Simmons | 74 | | | @ ASWC (D3) |
| Langston | 41 | at | Lyon | 14 | | | |
| East Texas Baptist | 59 | at | Southwestern Assemblies of God | 17 | | | ASWC (D3) |
| Panhandle State | 20 | at | Tarleton State | 48 | | | @ LSC (D2) |
| Millsaps | 29 | at | Texas Wesleyan | 13 | | | SAA (D3) |
| 9/16/2017 | Wayland Baptist | 12 | at | Arizona Christian | 42 | | | |
| Panhandle State | 31 | at | Bacone | 8 | | | |
| Texas Wesleyan | 7 | at | New Mexico Highlands | 42 | | | @ RMAC (D2) |
| Southwestern Assemblies of God | 52 | at | Texas College | 7 | | | |
| Lyon | 61 | at | Trinity Bible | 0 | | | @ None (Unk?) |
| 9/23/2017 | Bacone | 6 | vs | Langston | 36 | | Oklahoma City OK | |
| Lyon | 21 | at | Panhandle State | 42 | | | |
| Southwestern Assemblies of God | 42 | at | Texas Wesleyan | 7 | | | |
| Texas College | 23 | at | Wayland Baptist | 24 | | | |
| Arizona Christian | 56 | at | Whittier | 38 | | | @ SCIAC (D3) |
| 9/30/2017 | Texas College | 26 | at | Bacone | 31 | | | |
| Texas Wesleyan | 0 | at | Langston | 34 | | | |
| Wayland Baptist | 30 | at | Lyon | 28 | | | |
| Arizona Christian | 6 | at | Southwestern Assemblies of God | 43 | | | |
| 10/7/2017 | Lyon | 17 | at | Arizona Christian | 56 | | | |
| Langston | 27 | at | Lane | 21 | | | @ SIAC (D2) |
| Texas Wesleyan | 11 | at | Texas College | 21 | | | |
| Panhandle State | 35 | at | Wayland Baptist | 24 | | | |
| 10/14/2017 | Panhandle State | 33 | at | Arizona Christian | 28 | | | |
| Texas College | 17 | vs | Langston | 44 | | Tulsa OK | |
| Wayland Baptist | 31 | at | Southwestern Assemblies of God | 63 | | | |
| Bacone | 33 | at | Texas Wesleyan | 18 | | | |
| 10/21/2017 | Arizona Christian | 20 | at | Langston | 21 | | | |
| Texas Wesleyan | 14 | at | Lyon | 21 | | | |
| Southwestern Assemblies of God | 29 | at | Panhandle State | 21 | | | |
| Bacone | 21 | at | Wayland Baptist | 48 | | | |
| 10/28/2017 | Texas College | 0 | at | Arizona Christian | 56 | | | |
| Langston | 27 | at | Panhandle State | 14 | | | |
| Bacone | 17 | at | Prairie View | 34 | | | @ SWAC (1AA) |
| Lyon | 13 | at | Southwestern Assemblies of God | 28 | | | |
| Wayland Baptist | 54 | at | Texas Wesleyan | 24 | | | |
| 11/4/2017 | Bacone | 14 | at | Lyon | 34 | | | |
| Langston | 14 | at | Southwestern Assemblies of God | 10 | | | |
| Panhandle State | 34 | at | Texas College | 13 | | | |
| Arizona Christian | 63 | at | Texas Wesleyan | 7 | | | |
| 11/11/2017 | Southwestern Assemblies of God | 29 | at | Bacone | 8 | | | |
| Texas Wesleyan | 6 | at | Panhandle State | 65 | | | |
| Lyon | 41 | at | Texas College | 3 | | | |
| Langston | 38 | at | Wayland Baptist | 19 | | | |
| 11/18/2017 | Southwestern Assemblies of God | 28 | at | Campbellsville | 41 | | NCCAA Victory Bowl | @ MSC |
| Northwestern IA | 55 | at | Langston | 7 | | | GPAC |