| 8/25/2016 | Pikeville | 24 | at | Bluefield (1-10,1-9) | 20 | |||
| 9/1/2016 | Campbellsville (2-8,2-8) | 34 | at | Pikeville | 41 | |||
| 9/8/2016 | Pikeville | 14 | at | Eastern Kentucky (3-8) | 55 | at OVC | ||
| 9/17/2016 | Bethel TN (7-4,6-4) | 24 | at | Pikeville | 21 | |||
| 9/24/2016 | Reinhardt (13-1,10-0) | 62 | at | Pikeville | 7 | |||
| 10/1/2016 | Pikeville | 0 | at | Cumberland TN (5-6,5-4) | 21 | |||
| 10/15/2016 | Cincinnati Christian (0-11,0-10) | 0 | at | Pikeville | 59 | |||
| 10/22/2016 | Cumberlands KY (4-6,4-6) | 7 | at | Pikeville | 31 | |||
| 10/29/2016 | Pikeville | 7 | at | Union KY (5-6,5-5) | 20 | |||
| 11/5/2016 | Kentucky Christian (3-8,3-7) | 19 | at | Pikeville | 30 | |||
| 11/12/2016 | Pikeville | 10 | at | Georgetown KY (7-4,7-3) | 7 |
| vs Pikeville | vs Other Opponents | Pikeville compared to OOs | |
| Record: | 5-6 | 45-66 | |
| Points Scored: | 24.45 | 27.67 | 3.22 |
| Points Allowed: | 22.18 | 31.16 | -8.98 |
| Margin: | 2.27 | -3.49 | -5.76 |
| Total Points: | 46.63 | 58.83 | -12.20 |