| 8/25/2016 | Pikeville (6-5,6-4) | 24 | at | Bluefield | 20 | | | |
| 9/3/2016 | Bluefield | 7 | at | Campbell (5-5) | 59 | | | at Pio |
| 9/10/2016 | Bluefield | 13 | at | Faulkner (6-4,6-3) | 28 | | | |
| 9/17/2016 | Lindsey Wilson (11-2,9-1) | 62 | at | Bluefield | 23 | | | |
| 9/24/2016 | Campbellsville (2-8,2-8) | 48 | at | Bluefield | 34 | | | |
| 10/1/2016 | Bluefield | 3 | at | Reinhardt (13-1,10-0) | 64 | | | |
| 10/8/2016 | Bluefield | 7 | at | Georgetown KY (7-4,7-3) | 28 | | | |
| 10/22/2016 | Cincinnati Christian (0-11,0-10) | 7 | at | Bluefield | 28 | | | |
| 10/29/2016 | Bluefield | 13 | at | Cumberlands KY (4-6,4-6) | 28 | | | |
| 11/5/2016 | Union KY (5-6,5-5) | 7 | at | Bluefield | 0 | | | |
| 11/12/2016 | Bluefield | 3 | at | Kentucky Christian (3-8,3-7) | 20 | | | |