| 8/26/2016 | Dakota State (6-4) | 34 | at | Dakota Wesleyan | 30 | NSAA | ||
| 9/3/2016 | Tabor (8-3) | 21 | at | Dakota Wesleyan | 35 | KCAC | ||
| 9/10/2016 | Dakota Wesleyan | 55 | at | Jamestown (4-7) | 17 | at NSAA | ||
| 9/17/2016 | Doane (9-2,7-1) | 61 | at | Dakota Wesleyan | 34 | |||
| 9/24/2016 | Dakota Wesleyan | 39 | at | Hastings (4-7,1-7) | 20 | |||
| 10/8/2016 | Dakota Wesleyan | 42 | at | Dordt (5-6,2-6) | 37 | |||
| 10/15/2016 | Concordia NE (7-3,5-3) | 30 | at | Dakota Wesleyan | 52 | |||
| 10/22/2016 | Northwestern IA (4-6,4-4) | 27 | at | Dakota Wesleyan | 44 | |||
| 10/29/2016 | Morningside (10-2,8-0) | 39 | at | Dakota Wesleyan | 6 | |||
| 11/5/2016 | Dakota Wesleyan | 54 | at | Briar Cliff (1-10,0-8) | 24 | |||
| 11/12/2016 | Dakota Wesleyan | 42 | at | Midland U. (6-5,3-5) | 31 |
| vs Dakota Wesleyan | vs Other Opponents | Dakota Wesleyan compared to OOs | |
| Record: | 3-8 | 61-47 | |
| Points Scored: | 31.00 | 30.13 | -0.87 |
| Points Allowed: | 39.36 | 26.67 | 12.69 |
| Margin: | -8.36 | 3.46 | 11.82 |
| Total Points: | 70.36 | 56.80 | 13.56 |