| 9/3/2016 | Millikin (4-6) | 40 | at | Greenville | 21 | CCIW | ||
| 9/10/2016 | Greenville | 28 | at | Minnesota-Morris (6-4,5-4) | 33 | |||
| 9/17/2016 | Iowa Wesleyan (3-7,3-6) | 40 | at | Greenville | 37 | |||
| 9/24/2016 | Greenville | 14 | at | Westminster MO (4-6,4-5) | 35 | |||
| 10/1/2016 | Eureka (8-2,7-2) | 27 | at | Greenville | 13 | |||
| 10/8/2016 | Crown (2-8,2-7) | 33 | at | Greenville | 34 | |||
| 10/15/2016 | Greenville | 46 | at | MacMurray (8-2,7-2) | 59 | |||
| 10/22/2016 | Martin Luther (0-10,0-9) | 12 | at | Greenville | 63 | |||
| 10/29/2016 | Greenville | 14 | at | Northwestern MN (9-2,8-1) | 21 | |||
| 11/5/2016 | Greenville | 21 | at | St Scholastica (7-3,7-2) | 49 |
| vs Greenville | vs Other Opponents | Greenville compared to OOs | |
| Record: | 8-2 | 43-48 | |
| Points Scored: | 34.90 | 21.52 | -13.38 |
| Points Allowed: | 29.10 | 24.12 | 4.98 |
| Margin: | 5.80 | -2.60 | -8.40 |
| Total Points: | 64.00 | 45.64 | 18.36 |