| 9/3/2016 | Wisconsin-River Falls | 20 | at | Coe | 35 | WIAC | ||
| Bethel MN | 53 | at | Dubuque | 70 | MIA | |||
| Elmhurst | 28 | at | Loras | 27 | CCIW | |||
| Wisconsin-La Crosse | 45 | at | Luther | 14 | WIAC | |||
| Buena Vista | 33 | at | Mayville State | 42 | @ NSAA (NAIA) | |||
| McPherson | 29 | at | Nebraska Wesleyan | 34 | KCAC (NAIA) | |||
| Simpson | 30 | at | Wisconsin-Stout | 45 | @ WIAC | |||
| Central IA | 50 | at | Whitworth | 49 | OT | @ NWC | ||
| 9/10/2016 | Central IA | 45 | at | Augustana IL | 17 | @ CCIW | ||
| Loras | 9 | at | Aurora | 14 | @ NAC | |||
| St John's MN | 40 | at | Buena Vista | 17 | MIA | |||
| Coe | 63 | at | Cornell IA | 6 | @ MidW | |||
| Simpson | 25 | at | Illinois College | 23 | @ MidW | |||
| Wartburg | 22 | at | Monmouth IL | 29 | @ MidW | |||
| Illinois Wesleyan | 17 | at | Nebraska Wesleyan | 13 | CCIW | |||
| Dubuque | 28 | at | Pacific | 24 | @ NWC | |||
| Luther | 46 | at | St Olaf | 40 | 2OT | @ MIA | ||
| 9/17/2016 | Buena Vista | 0 | at | Central IA | 33 | |||
| Loras | 10 | at | Coe | 45 | 2OT | |||
| Simpson | 20 | at | Dubuque | 41 | ||||
| Wartburg | 38 | at | Nebraska Wesleyan | 28 | ||||
| 9/24/2016 | Simpson | 17 | at | Buena Vista | 9 | |||
| Central IA | 42 | at | Loras | 34 | ||||
| Dubuque | 30 | at | Luther | 17 | ||||
| Coe | 48 | at | Nebraska Wesleyan | 17 | ||||
| Finlandia | 0 | at | Wartburg | 56 | D3Ind | |||
| 10/1/2016 | Dubuque | 35 | at | Central IA | 17 | |||
| Wartburg | 34 | at | Coe | 37 | ||||
| Buena Vista | 34 | at | Loras | 24 | ||||
| Nebraska Wesleyan | 27 | at | Luther | 24 | ||||
| 10/8/2016 | Central IA | 30 | at | Coe | 33 | |||
| Nebraska Wesleyan | 23 | at | Dubuque | 42 | ||||
| Luther | 24 | at | Simpson | 17 | ||||
| Loras | 30 | at | Wartburg | 38 | ||||
| 10/15/2016 | Luther | 24 | at | Buena Vista | 48 | |||
| Coe | 23 | at | Dubuque | 12 | ||||
| Central IA | 43 | at | Nebraska Wesleyan | 17 | ||||
| Simpson | 6 | at | Wartburg | 20 | ||||
| 10/22/2016 | Dubuque | 45 | at | Buena Vista | 37 | 3OT | ||
| Wartburg | 37 | at | Central IA | 51 | ||||
| Coe | 45 | at | Luther | 6 | ||||
| Loras | 0 | at | Simpson | 30 | ||||
| 10/29/2016 | Buena Vista | 7 | at | Coe | 48 | |||
| Wartburg | 43 | at | Dubuque | 35 | ||||
| Luther | 28 | at | Loras | 43 | ||||
| Nebraska Wesleyan | 24 | at | Simpson | 22 | ||||
| 11/5/2016 | Nebraska Wesleyan | 31 | at | Buena Vista | 38 | |||
| Simpson | 14 | at | Central IA | 49 | ||||
| Dubuque | 60 | at | Loras | 22 | ||||
| Luther | 28 | at | Wartburg | 27 | OT | |||
| 11/12/2016 | Central IA | 37 | at | Luther | 23 | |||
| Loras | 27 | at | Nebraska Wesleyan | 51 | ||||
| Coe | 47 | at | Simpson | 29 | ||||
| Buena Vista | 14 | at | Wartburg | 42 | ||||
| 11/19/2016 | Monmouth IL | 14 | at | Coe | 21 | MidW | ||
| 11/26/2016 | Coe | 6 | at | St Thomas | 55 | @ MIA |