| 9/5/2015 | Mercer | 28 | at | Austin Peay (0-11) | 7 | at OVC | ||
| 9/12/2015 | Stetson (3-8) | 14 | at | Mercer | 57 | Pio | ||
| 9/19/2015 | Mercer | 22 | at | Tennessee Tech (4-7) | 29 | at OVC | ||
| 10/3/2015 | Wofford (5-6,3-4) | 34 | at | Mercer | 33 | OT | ||
| 10/10/2015 | Mercer | 21 | at | Western Carolina (7-4,5-2) | 24 | |||
| 10/17/2015 | East Tennessee St (2-9) | 0 | at | Mercer | 52 | IndFCS | ||
| 10/24/2015 | VMI (2-9,1-6) | 28 | at | Mercer | 21 | |||
| 10/31/2015 | Mercer | 19 | at | The Citadel (9-4,6-1) | 21 | |||
| 11/7/2015 | Chattanooga (9-4,6-1) | 14 | at | Mercer | 17 | |||
| 11/14/2015 | Mercer | 27 | at | Furman (4-7,2-5) | 20 | OT | ||
| 11/21/2015 | Samford (6-5,3-4) | 47 | at | Mercer | 21 |
| vs Mercer | vs Other Opponents | Mercer compared to OOs | |
| Record: | 6-5 | 45-69 | |
| Points Scored: | 21.64 | 24.24 | 2.60 |
| Points Allowed: | 28.91 | 30.25 | -1.34 |
| Margin: | -7.27 | -6.01 | 1.26 |
| Total Points: | 50.55 | 54.49 | -3.94 |