| 9/3/2015 | Central Arkansas (7-4) | 16 | at | Samford | 45 | SLC | ||
| 9/12/2015 | Florida A&M (1-10) | 21 | at | Samford | 58 | MEAC | ||
| 9/19/2015 | Chattanooga (9-4,6-1) | 31 | at | Samford | 21 | |||
| 9/26/2015 | Samford | 3 | at | Louisville (8-5) | 45 | at ACC | ||
| 10/10/2015 | Samford | 49 | at | VMI (2-9,1-6) | 13 | |||
| 10/17/2015 | The Citadel (9-4,6-1) | 44 | at | Samford | 25 | |||
| 10/24/2015 | Samford | 36 | at | Western Carolina (7-4,5-2) | 56 | |||
| 10/31/2015 | Furman (4-7,2-5) | 20 | at | Samford | 17 | |||
| 11/7/2015 | Clark Atlanta (1-8) | 0 | at | Samford | 43 | SIAC (D2) | ||
| 11/14/2015 | Samford | 37 | at | Wofford (5-6,3-4) | 27 | |||
| 11/21/2015 | Samford | 47 | at | Mercer (5-6,2-5) | 21 |
| vs Samford | vs Other Opponents | Samford compared to OOs | |
| Record: | 5-6 | 53-61 | |
| Points Scored: | 26.73 | 24.33 | -2.40 |
| Points Allowed: | 34.64 | 26.18 | 8.46 |
| Margin: | -7.91 | -1.85 | 6.06 |
| Total Points: | 61.37 | 50.51 | 10.86 |