| 9/5/2015 | Olivet Nazarene (3-8,2-8) | 16 | at | St Francis IN | 59 | | | |
| 9/12/2015 | St Francis IN | 48 | at | Taylor (7-3,6-2) | 42 | | | |
| 9/19/2015 | Trinity International (2-9,0-9) | 3 | at | St Francis IN | 45 | | | |
| 9/26/2015 | St Francis IN | 74 | at | Lindenwood-Belleville (4-6,4-6) | 13 | | | |
| 10/3/2015 | St Francis IN | 45 | at | Marian IN (12-2,8-2) | 42 | | | |
| 10/10/2015 | Siena Heights (4-6,4-6) | 25 | at | St Francis IN | 49 | | | |
| 10/17/2015 | Concordia MI (5-6,4-6) | 7 | at | St Francis IN | 48 | | | |
| 10/24/2015 | St Francis IN | 38 | at | Robert Morris IL (6-4,4-4) | 29 | | | |
| 11/14/2015 | St Francis IN | 64 | at | Missouri Baptist (0-10,0-9) | 6 | | | |
| 11/21/2015 | Reinhardt (9-2) | 26 | at | St Francis IN | 37 | | NAIA FCS First Round | MSC |
| 11/28/2015 | Montana Tech (10-2) | 20 | at | St Francis IN | 42 | | NAIA Quarterfinal | Front |
| 12/5/2015 | Marian IN (12-2,8-2) | 45 | at | St Francis IN | 14 | | NAIA Semifinal | |