| 9/3/2015 | Chadron State (5-6) | 40 | at | Missouri S&T | 27 | RMAC | ||
| 9/12/2015 | Missouri S&T | 20 | at | Texas A&M-Kingsville (2-9) | 38 | at LSC | ||
| 9/19/2015 | Missouri S&T | 10 | at | Truman State (5-6,4-4) | 7 | |||
| 9/26/2015 | St Joseph's (4-6,3-5) | 27 | at | Missouri S&T | 39 | |||
| 10/3/2015 | Missouri S&T | 16 | at | William Jewell (4-7,4-4) | 40 | |||
| 10/17/2015 | Missouri S&T | 40 | at | Lincoln MO (1-10,0-8) | 23 | |||
| 10/24/2015 | McKendree (8-2,6-2) | 27 | at | Missouri S&T | 34 | |||
| 10/31/2015 | Southwest Baptist (4-6,3-5) | 46 | at | Missouri S&T | 42 | |||
| 11/7/2015 | Missouri S&T | 14 | at | Indianapolis (10-2,8-0) | 38 | |||
| 11/14/2015 | Quincy (3-7,3-5) | 35 | at | Missouri S&T | 42 |
| vs Missouri S&T | vs Other Opponents | Missouri S&T compared to OOs | |
| Record: | 5-5 | 41-56 | |
| Points Scored: | 32.10 | 26.70 | -5.40 |
| Points Allowed: | 28.40 | 28.64 | -0.24 |
| Margin: | 3.70 | -1.94 | -5.64 |
| Total Points: | 60.50 | 55.34 | 5.16 |