| 9/1/2012 | Bridgewater VA (7-3) | 23 | at | St Vincent | 7 | ODC | ||
| 9/8/2012 | Wooster (2-8) | 27 | at | St Vincent | 21 | OT | NCA | |
| 9/15/2012 | Waynesburg (10-1,7-1) | 35 | at | St Vincent | 14 | |||
| 9/22/2012 | St Vincent | 6 | at | Westminster PA (3-6,2-6) | 17 | |||
| 10/6/2012 | Thiel (3-7,3-5) | 14 | at | St Vincent | 7 | |||
| 10/13/2012 | Geneva (3-7,3-5) | 30 | at | St Vincent | 22 | |||
| 10/20/2012 | St Vincent | 14 | at | Washington & Jefferson (8-3,7-1) | 40 | |||
| 10/27/2012 | St Vincent | 3 | at | Thomas More (7-3,6-2) | 38 | |||
| 11/3/2012 | Grove City (6-4,5-3) | 27 | at | St Vincent | 10 | |||
| 11/10/2012 | St Vincent | 27 | at | Bethany WV (3-7,3-5) | 54 |
| vs St Vincent | vs Other Opponents | St Vincent compared to OOs | |
| Record: | 10-0 | 42-49 | |
| Points Scored: | 30.50 | 23.60 | -6.90 |
| Points Allowed: | 13.10 | 22.76 | -9.66 |
| Margin: | 17.40 | 0.84 | -16.56 |
| Total Points: | 43.60 | 46.36 | -2.76 |