| 9/8/2012 | Midwestern State (9-2,7-1) | 17 | at | Tarleton State | 20 | |||
| 9/15/2012 | Abilene Christian (7-4,4-4) | 34 | vs | Tarleton State | 31 | Arlington TX | ||
| 9/22/2012 | Eastern New Mexico (3-7,2-6) | 23 | at | Tarleton State | 35 | |||
| 9/29/2012 | Tarleton State | 21 | at | West Texas A&M (12-3,7-1) | 41 | |||
| 10/6/2012 | Delta State (3-7) | 38 | at | Tarleton State | 35 | GSC | ||
| 10/13/2012 | Tarleton State | 43 | at | Texas A&M-Commerce (1-9,1-7) | 10 | |||
| 10/20/2012 | Texas A&M-Kingsville (6-6,5-3) | 35 | at | Tarleton State | 23 | |||
| 10/27/2012 | Tarleton State | 45 | at | Incarnate Word (2-9,1-7) | 20 | |||
| 11/3/2012 | Tarleton State | 38 | at | North Alabama (5-5) | 28 | at GSC | ||
| 11/10/2012 | Angelo State (5-6,4-4) | 37 | at | Tarleton State | 54 |
| vs Tarleton State | vs Other Opponents | Tarleton State compared to OOs | |
| Record: | 4-6 | 49-52 | |
| Points Scored: | 28.30 | 26.32 | -1.98 |
| Points Allowed: | 34.50 | 26.36 | 8.14 |
| Margin: | -6.20 | -0.04 | 6.16 |
| Total Points: | 62.80 | 52.68 | 10.12 |