| 9/1/2012 | Western State (1-10) | 14 | at | Angelo State | 42 | RMAC | ||
| 9/8/2012 | Chadron State (9-3) | 19 | at | Angelo State | 7 | RMAC | ||
| 9/15/2012 | Valdosta State (12-2) | 43 | vs | Angelo State | 10 | Arlington TX | GSC | |
| 9/22/2012 | Abilene Christian (7-4,4-4) | 23 | at | Angelo State | 28 | |||
| 9/29/2012 | Angelo State | 49 | at | Eastern New Mexico (3-7,2-6) | 19 | |||
| 10/6/2012 | West Texas A&M (12-3,7-1) | 35 | at | Angelo State | 9 | |||
| 10/13/2012 | Angelo State | 28 | at | Midwestern State (9-2,7-1) | 35 | |||
| 10/20/2012 | Texas A&M-Commerce (1-9,1-7) | 16 | at | Angelo State | 17 | |||
| 10/27/2012 | Angelo State | 21 | at | Texas A&M-Kingsville (6-6,5-3) | 34 | |||
| 11/3/2012 | Incarnate Word (2-9,1-7) | 21 | at | Angelo State | 38 | |||
| 11/10/2012 | Angelo State | 37 | at | Tarleton State (6-4,5-3) | 54 |
| vs Angelo State | vs Other Opponents | Angelo State compared to OOs | |
| Record: | 6-5 | 62-54 | |
| Points Scored: | 28.45 | 28.38 | -0.07 |
| Points Allowed: | 26.00 | 26.50 | -0.50 |
| Margin: | 2.45 | 1.88 | -0.57 |
| Total Points: | 54.45 | 54.88 | -0.43 |