| 9/1/2012 | Prairie View | 41 | at | Texas Southern (2-9,2-7) | 44 | |||
| 9/8/2012 | Prairie View | 0 | at | Lamar (4-8) | 31 | at SLC | ||
| 9/15/2012 | Prairie View | 30 | at | Alabama A&M (7-4,6-3) | 42 | |||
| 9/22/2012 | Prairie View | 7 | at | North Dakota State (14-1) | 66 | at MVC | ||
| 9/29/2012 | Prairie View | 13 | at | Jackson State (7-5,7-3) | 34 | |||
| 10/6/2012 | Grambling (1-10,0-9) | 14 | vs | Prairie View | 31 | Dallas TX | ||
| 10/20/2012 | Alcorn State (4-7,4-5) | 37 | at | Prairie View | 52 | |||
| 10/27/2012 | Prairie View | 49 | vs | Southern (4-7,3-6) | 29 | Shreveport LA | ||
| 11/3/2012 | Alabama State (7-4,7-2) | 35 | at | Prairie View | 21 | |||
| 11/10/2012 | Prairie View | 20 | at | Mississippi Valley State (5-6,5-4) | 22 | |||
| 11/17/2012 | Prairie View | 41 | at | Ark Pine Bluff (10-2,9-1) | 42 |
| vs Prairie View | vs Other Opponents | Prairie View compared to OOs | |
| Record: | 8-3 | 57-60 | |
| Points Scored: | 36.00 | 22.30 | -13.70 |
| Points Allowed: | 27.73 | 24.96 | 2.77 |
| Margin: | 8.27 | -2.66 | -10.93 |
| Total Points: | 63.73 | 47.26 | 16.47 |