| 9/15/2012 | Pennsylvania | 21 | at | Lafayette (5-6) | 28 | at Pat | ||
| 9/22/2012 | Villanova (8-4) | 24 | at | Pennsylvania | 8 | CAAF | ||
| 9/29/2012 | Pennsylvania | 28 | at | Dartmouth (6-4,4-3) | 21 | |||
| 10/6/2012 | William & Mary (2-9) | 34 | at | Pennsylvania | 28 | CAAF | ||
| 10/13/2012 | Columbia (3-7,2-5) | 20 | at | Pennsylvania | 24 | |||
| 10/20/2012 | Pennsylvania | 13 | at | Yale (2-8,1-6) | 27 | |||
| 10/27/2012 | Brown (7-3,4-3) | 17 | at | Pennsylvania | 20 | |||
| 11/3/2012 | Pennsylvania | 28 | at | Princeton (5-5,4-3) | 21 | |||
| 11/10/2012 | Harvard (8-2,5-2) | 21 | at | Pennsylvania | 30 | |||
| 11/17/2012 | Pennsylvania | 35 | at | Cornell (4-6,2-5) | 28 |
| vs Pennsylvania | vs Other Opponents | Pennsylvania compared to OOs | |
| Record: | 4-6 | 46-48 | |
| Points Scored: | 24.10 | 24.51 | 0.41 |
| Points Allowed: | 23.50 | 23.32 | 0.18 |
| Margin: | 0.60 | 1.19 | 0.59 |
| Total Points: | 47.60 | 47.83 | -0.23 |