| 9/8/2012 | Lafayette | 17 | at | William & Mary (2-9) | 14 | at CAAF | ||
| 9/15/2012 | Pennsylvania (6-4) | 21 | at | Lafayette | 28 | Ivy | ||
| 9/22/2012 | Lafayette | 20 | at | Bucknell (3-8,1-5) | 14 | |||
| 9/29/2012 | Lafayette | 28 | at | Robert Morris (4-7) | 31 | at NE | ||
| 10/6/2012 | Princeton (5-5) | 35 | at | Lafayette | 14 | Ivy | ||
| 10/13/2012 | Lafayette | 20 | at | Yale (2-8) | 10 | at Ivy | ||
| 10/20/2012 | Holy Cross (2-9,2-4) | 13 | at | Lafayette | 30 | |||
| 10/27/2012 | Georgetown (5-6,2-4) | 20 | at | Lafayette | 17 | |||
| 11/3/2012 | Lafayette | 41 | at | Colgate (8-4,6-0) | 65 | |||
| 11/10/2012 | Lafayette | 27 | at | Fordham (6-5,3-3) | 36 | |||
| 11/17/2012 | Lehigh (10-1,5-1) | 38 | at | Lafayette | 21 |
| vs Lafayette | vs Other Opponents | Lafayette compared to OOs | |
| Record: | 6-5 | 47-61 | |
| Points Scored: | 27.00 | 23.66 | -3.34 |
| Points Allowed: | 23.91 | 25.89 | -1.98 |
| Margin: | 3.09 | -2.23 | -5.32 |
| Total Points: | 50.91 | 49.55 | 1.36 |