| 9/11/2010 | Merchant Marine Mariners 8 @ Coast Guard 10 | |
| 9/18/2010 | Coast Guard 0 @ Curry Colonels 35 | † |
| 9/25/2010 | Coast Guard 16 @ Massachusetts Maritime Buccaneers 23 | † |
| 10/2/2010 | Fitchburg State Falcons 7 @ Coast Guard 19 | † |
| 10/9/2010 | Bridgewater State MA Bears 32 @ Coast Guard 25 2OT | † |
| 10/16/2010 | Coast Guard 15 @ Westfield State Owls 26 | † |
| 10/23/2010 | Coast Guard 7 @ Worcester State Lancers 31 | † |
| 10/30/2010 | Framingham State Rams 34 @ Coast Guard 13 | † |
| 11/6/2010 | Maine Maritime Mariners 63 @ Coast Guard 47 | † |