| 9/4/2010 | C W Post 20 @ American Int'l Yellow Jackets 11 | |
| 9/11/2010 | California PA Vulcans 40 @ C W Post 13 | † |
| 9/18/2010 | Mercyhurst Lakers 28 @ C W Post 20 | † |
| 9/25/2010 | C W Post 31 @ Shippensburg Red Raiders 14 | † |
| 10/2/2010 | C W Post 39 @ West Chester Golden Rams 37 | † |
| 10/9/2010 | Millersville Marauders 21 @ C W Post 49 | † |
| 10/16/2010 | East Stroudsburg Warriors 17 @ C W Post 28 | † |
| 10/23/2010 | C W Post 48 @ Kutztown Golden Bears 50 | † |
| 10/30/2010 | Bloomsburg Huskies 36 @ C W Post 16 | † |
| 11/6/2010 | C W Post 63 @ Cheyney Wolves 28 | † |
| 11/13/2010 | C W Post 42 @ Slippery Rock Rockets 38 | † |