| 8/28/2010 | Washburn 34 @ Colorado Mines Orediggers 29 | |
| 9/4/2010 | Abilene Christian Wildcats 34 @ Washburn 26 | |
| 9/18/2010 | Missouri Western Griffons 36 @ Washburn 33 | † |
| 9/25/2010 | Washburn 45 @ Central Missouri Mules 55 | † |
| 10/2/2010 | Washburn 38 @ Fort Hays State Tigers 27 | † |
| 10/9/2010 | Nebraska-Omaha Mavericks 28 @ Washburn 40 | † |
| 10/16/2010 | Washburn 35 @ Pittsburg State Gorillas 34 2OT | † |
| 10/23/2010 | Northwest Missouri State Bearcats 41 @ Washburn 40 | † |
| 10/30/2010 | Washburn 45 @ Truman State Bulldogs 12 | † |
| 11/6/2010 | Emporia State Hornets 0 @ Washburn 42 | † |
| 11/13/2010 | Washburn 23 @ Missouri Southern Lions 7 | † |
| 12/4/2010 | Midwestern State Mustangs 14 vs Washburn 45 (Topeka KS) |