| 9/4/2010 | Morehead St | @ | James Madison | ||||||
| 9/11/2010 | James Madison | @ | Virginia Tech | ||||||
| 9/25/2010 | Liberty | @ | James Madison | ||||||
| 10/2/2010 | Delaware | @ | James Madison | CAAF | |||||
| 10/9/2010 | James Madison | @ | Towson | CAAF | |||||
| 10/16/2010 | New Hampshire | @ | James Madison | CAAF | |||||
| 10/23/2010 | James Madison | @ | Villanova | CAAF | |||||
| 10/30/2010 | Massachusetts | @ | James Madison | CAAF | |||||
| 11/6/2010 | James Madison | @ | Richmond | CAAF | |||||
| 11/13/2010 | William & Mary | @ | James Madison | CAAF | |||||
| 11/20/2010 | James Madison | @ | Maine | CAAF |