| 9/4/2010 | Chicago @ Beloit | |
| 9/4/2010 | John Carroll @ Case Western Reserve | |
| 9/4/2010 | Carnegie Mellon @ Grove City | |
| 9/4/2010 | Knox @ Washington U | |
| 9/11/2010 | Carnegie Mellon @ Allegheny | |
| 9/11/2010 | Concordia IL @ Chicago | |
| 9/11/2010 | Washington U @ Rhodes | |
| 9/11/2010 | Case Western Reserve @ Rochester | |
| 9/18/2010 | Hobart @ Carnegie Mellon | |
| 9/18/2010 | Chicago @ Elmhurst | |
| 9/18/2010 | Washington U @ Wittenberg | |
| 9/25/2010 | Kenyon @ Carnegie Mellon | |
| 9/25/2010 | Denison @ Case Western Reserve | |
| 9/25/2010 | Chicago @ Wabash | |
| 9/25/2010 | Westminster MO @ Washington U | |
| 10/2/2010 | Hiram @ Carnegie Mellon | |
| 10/2/2010 | Allegheny @ Case Western Reserve | |
| 10/2/2010 | Ohio Wesleyan @ Chicago | |
| 10/9/2010 | Denison @ Chicago | |
| 10/9/2010 | Case Western Reserve @ Oberlin | |
| 10/9/2010 | Carnegie Mellon @ Ohio Wesleyan | |
| 10/9/2010 | Wabash @ Washington U | |
| 10/16/2010 | Case Western Reserve @ Hiram | |
| 10/16/2010 | Washington U @ Wooster | |
| 10/23/2010 | Wittenberg @ Carnegie Mellon | |
| 10/23/2010 | Wooster @ Case Western Reserve | |
| 10/23/2010 | Chicago @ Kenyon | |
| 10/23/2010 | Oberlin @ Washington U | |
| 10/30/2010 | Case Western Reserve @ Chicago | † |
| 10/30/2010 | Carnegie Mellon @ Washington U | † |
| 11/6/2010 | Chicago @ Carnegie Mellon | † |
| 11/6/2010 | Washington U @ Case Western Reserve | † |
| 11/13/2010 | Carnegie Mellon @ Case Western Reserve | † |
| 11/13/2010 | Washington U @ Chicago | † |