11 Jan 2011 5:05pm (US Central)
| 0-1 | — | 0 | (1 Common Ops) | 0 | Cincinnati | 4-8 |
| L 14-59 at | 9/4/2010 | South Florida (6-5) | 10/22/2010 | L 30-38 |
|
| 0-1 | — | 0 | (1 Common Ops) | 0 | Clemson | 6-7 |
| L 14-59 at | 9/4/2010 | South Florida (6-5) | 12/31/2010 | L 26-31 vs |
|
| 0-1 | — | 0 | (1 Common Ops) | 0 | Connecticut | 8-5 |
| L 14-59 at | 9/4/2010 | South Florida (7-4) | 12/4/2010 | W 19-16 at |
|
| 0-1 | — | 0 | (1 Common Ops) | 0 | Florida | 8-5 |
| L 14-59 at | 9/4/2010 | South Florida (7-4) | 9/11/2010 | W 38-14 |
|
| 0-1 | — | 0 | (1 Common Ops) | 0 | Florida Atlantic | 4-8 |
| L 14-59 at | 9/4/2010 | South Florida (6-5) | 10/2/2010 | L 3-21 at |
|
| 0-1 | — | 0 | (1 Common Ops) | 0 | Louisville | 7-6 |
| L 14-59 at | 9/4/2010 | South Florida (6-5) | 11/13/2010 | L 21-24 1 |
|
| 0-1 | — | 0 | (1 Common Ops) | 0 | Miami-Florida | 7-6 |
| L 14-59 at | 9/4/2010 | South Florida (6-5) | 11/27/2010 | L 20-23 1 |
|
| 0-1 | — | 0 | (1 Common Ops) | 0 | Pittsburgh | 8-5 |
| L 14-59 at | 9/4/2010 | South Florida (7-4) | 11/20/2010 | W 17-10 at |
|
| 0-1 | — | 0 | (1 Common Ops) | 0 | Rutgers | 4-8 |
| L 14-59 at | 9/4/2010 | South Florida (6-5) | 11/3/2010 | L 27-28 at |
|
| 0-1 | — | 0 | (1 Common Ops) | 0 | Syracuse | 8-5 |
| L 14-59 at | 9/4/2010 | South Florida (7-4) | 10/9/2010 | W 13-9 at |
|
| 0-1 | — | 0 | (1 Common Ops) | 0 | West Virginia | 9-4 |
| L 14-59 at | 9/4/2010 | South Florida (7-4) | 10/14/2010 | W 20-6 |
|
| 0-1 | — | 0 | (1 Common Ops) | 0 | Western Kentucky | 2-10 |
| L 14-59 at | 9/4/2010 | South Florida (6-5) | 9/25/2010 | L 12-24 at |
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