11 Jan 2011 5:04pm (US Central)
| 0-1 | — | 0 | (1 Common Ops) | 0 | Arkansas State | 4-8 |
| L 13-23 at | 9/11/2010 | Louisville (5-6) | 10/2/2010 | L 24-34 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Cincinnati | 4-8 |
| L 13-23 at | 9/11/2010 | Louisville (6-5) | 10/15/2010 | W 35-27 at |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Connecticut | 8-5 |
| L 13-23 at | 9/11/2010 | Louisville (5-6) | 10/23/2010 | L 0-26 at |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Kentucky | 6-7 |
| L 13-23 at | 9/11/2010 | Louisville (6-5) | 9/4/2010 | W 23-16 at |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Memphis | 1-11 |
| L 13-23 at | 9/11/2010 | Louisville (5-6) | 10/9/2010 | L 0-56 at |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Oregon State | 5-7 |
| L 13-23 at | 9/11/2010 | Louisville (6-5) | 9/18/2010 | W 35-28 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Pittsburgh | 8-5 |
| L 13-23 at | 9/11/2010 | Louisville (6-5) | 10/30/2010 | W 21-3 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Rutgers | 4-8 |
| L 13-23 at | 9/11/2010 | Louisville (5-6) | 11/26/2010 | L 13-40 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | South Florida | 8-5 |
| L 13-23 at | 9/11/2010 | Louisville (6-5) | 11/13/2010 | W 24-21 1 at |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Southern Miss | 8-5 |
| L 13-23 at | 9/11/2010 | Louisville (5-6) | 12/21/2010 | L 28-31 vs |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Syracuse | 8-5 |
| L 13-23 at | 9/11/2010 | Louisville (5-6) | 11/6/2010 | L 20-28 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | West Virginia | 9-4 |
| L 13-23 at | 9/11/2010 | Louisville (6-5) | 11/20/2010 | W 17-10 at |
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