| 8/30/2008 | McNeese St | 27 | @ | North Carolina | 35 | ||||
| 9/6/2008 | Delta St D2 | 27 | @ | McNeese St | 52 | ||||
| 9/27/2008 | Southern Virginia NAIA | 7 | @ | McNeese St | 63 | ||||
| 10/4/2008 | McNeese St | 46 | @ | S Dakota St | 44 | 2 OT | |||
| 10/11/2008 | Texas St | 45 | @ | McNeese St | 42 | SLC | |||
| 10/18/2008 | McNeese St | 28 | @ | Sam Houston | 17 | SLC | |||
| 10/25/2008 | Nicholls St | 38 | @ | McNeese St | 35 | SLC | |||
| 11/1/2008 | McNeese St | 24 | @ | SE Louisiana | 14 | SLC | |||
| 11/8/2008 | SF Austin | 31 | @ | McNeese St | 42 | SLC | |||
| 11/15/2008 | McNeese St | 24 | @ | Northwestern St | 17 | SLC | |||
| 11/22/2008 | McNeese St | 30 | @ | Central Arkansas | 47 | SLC |