| 9/6/2008 | Butler | 20 | @ | Albion D3 | 6 | ||||
| 9/13/2008 | Franklin D3 | 31 | @ | Butler | 28 | ||||
| 9/27/2008 | Butler | 41 | @ | Missouri S&T D2 | 15 | ||||
| 10/4/2008 | Drake | 15 | @ | Butler | 21 | Pio | |||
| 10/11/2008 | Butler | 56 | @ | Campbell | 7 | Pio | |||
| 10/18/2008 | Butler | 48 | @ | Valparaiso | 21 | Pio | |||
| 10/25/2008 | Morehead St | 21 | @ | Butler | 31 | Pio | |||
| 11/1/2008 | Jacksonville | 45 | @ | Butler | 9 | Pio | |||
| 11/8/2008 | Dayton | 28 | @ | Butler | 21 | OT | Pio | ||
| 11/15/2008 | Butler | 17 | @ | San Diego | 34 | Pio | |||
| 11/22/2008 | Butler | 34 | @ | Davidson | 46 | Pio |