| Thursday, 29 Nov 2007 | |||||||
| BigE | Rutgers | 38 | @ | Louisville | 41 | ||
| Friday, 30 Nov 2007 | |||||||
| WAC | Fresno St | 30 | @ | New Mexico St | 23 | ||
| Saturday, 1 Dec 2007 | |||||||
| Eastern Washington | 35 | @ | Appalachian St | 38 | FCS Quarterfinals | ||
| P10 | Arizona | 17 | @ | Arizona St | 20 | ||
| Shepherd (D2) | 38 | @ | California PA (D2) | 58 | D2 Playoffs | ||
| St Francis IN (NAIA) | 7 | @ | Carroll MT (NAIA) | 23 | NAIA Semifinals | ||
| CUSA | Tulsa | 25 | @ | Central Florida | 44 | CUSA Title | |
| Bethel MN (D3) | 27 | @ | Central IA (D3) | 7 | D3 Playoffs | ||
| MAC | Miami OH | 10 | vs | Central Michigan | 35 | MAC Title - Detroit MI | |
| NW Missouri St (D2) | 26 | @ | Chadron St (D2) | 13 | D2 Playoffs | ||
| Western Oregon (D2) | 26 | vs | Colorado Mines (D2) | 12 | Rotary Bowl | ||
| Albany | 21 | @ | Dayton | 42 | |||
| SBC | North Texas | 19 | @ | Florida Int'l | 38 | ||
| Central Washington (D2) | 21 | @ | Grand Valley St (D2) | 41 | D2 Playoffs | ||
| Washington | 21 | @ | Hawaii | 28 | |||
| SEC | Tennessee | 14 | vs | LSU | 21 | SEC Title - Atlanta GA | |
| Wayne St NE (D2) | 13 | @ | Missouri Western (D2) | 20 | D2 Playoffs | ||
| St John Fisher (D3) | 10 | @ | Mount Union (D3) | 52 | D3 Playoffs | ||
| Ind | Navy | 38 | vs | Army | 3 | Baltimore MD | |
| WAC | Louisiana Tech | 10 | @ | Nevada | 49 | ||
| Delaware | 39 | @ | Northern Iowa | 27 | FCS Quarterfinals | ||
| B12 | Oklahoma | 38 | vs | Missouri | 17 | Big 12 Title - San Antonio TX | |
| P10 | Oregon St | 38 | @ | Oregon | 31 | 2OT | |
| MW | Brigham Young | 48 | @ | San Diego St | 27 | ||
| Missouri Valley (NAIA) (10-2) | @ | Sioux Falls (NAIA) (12-0) | ppd, NAIA Semifinals | ||||
| P10 | UCLA | 7 | @ | Southern Cal | 24 | ||
| Massachusetts | 27 | @ | Southern Illinois | 34 | FCS Quarterfinals | ||
| P10 | California | 13 | @ | Stanford | 20 | ||
| SBC | Florida Atlantic | 38 | @ | Troy | 32 | ||
| Tuskegee (D2) | 58 | vs | Virginia Union (D2) | 51 | Columbia SC | ||
| Wabash (D3) | 7 | @ | UW-Whitewater (D3) | 47 | D3 Playoffs | ||
| GSC | North Alabama (D2) | 23 | @ | Valdosta St (D2) | 37 | D2 Playoffs | |
| ACC | Virginia Tech | 30 | vs | Boston College | 16 | ACC Title | |
| Mary Hardin-Baylor (D3) | 27 | @ | Wesley (D3) | 10 | D3 Playoffs | ||
| BigE | Pittsburgh | 13 | @ | West Virginia | 9 | ||
| Richmond | 21 | @ | Wofford | 10 | FCS Quarterfinals | ||