| 9/1/2005 | Slippery Rock | 14 | @ | Youngstown St | 44 | ||||
| 9/10/2005 | Northeastern | 16 | @ | Youngstown St | 35 | ||||
| 9/17/2005 | Youngstown St | 42 | @ | Liberty | 0 | ||||
| 9/24/2005 | Youngstown St | 0 | @ | Pittsburgh | 41 | ||||
| 10/1/2005 | Illinois St | 17 | @ | Youngstown St | 20 | GW | |||
| 10/8/2005 | Youngstown St | 45 | @ | Indiana St | 0 | GW | |||
| 10/15/2005 | Western Illinois | 21 | @ | Youngstown St | 23 | GW | |||
| 10/22/2005 | Missouri State | 7 | @ | Youngstown St | 31 | GW | |||
| 10/29/2005 | Youngstown St | 7 | @ | Northern Iowa | 21 | GW | |||
| 11/5/2005 | Youngstown St | 17 | @ | Southern Illinois | 31 | GW | |||
| 11/12/2005 | Western Kentucky | 10 | @ | Youngstown St | 42 | GW |