| 9/3/2005 | Winston-Salem St | 6 | @ | Howard | 20 | ||||
| 9/10/2005 | Hampton | 22 | @ | Howard | 12 | MEAC | |||
| 9/17/2005 | Howard | 20 | @ | Florida A&M | 33 | MEAC | |||
| 9/24/2005 | Howard | 39 | @ | Savannah St | 21 | ||||
| 10/1/2005 | Howard | 27 | @ | Charleston So | 22 | ||||
| 10/15/2005 | Howard | 0 | @ | Morgan St | 7 | MEAC | |||
| 10/22/2005 | NC A&T | 0 | @ | Howard | 16 | MEAC | |||
| 10/29/2005 | Howard | 7 | @ | Norfolk St | 26 | MEAC | |||
| 11/5/2005 | S Carolina St | 23 | @ | Howard | 9 | MEAC | |||
| 11/12/2005 | Bethune-Cookman | 45 | @ | Howard | 16 | MEAC | |||
| 11/19/2005 | Howard | 7 | @ | Delaware St | 23 | MEAC |