| 9/3/2005 | Jackson St | 7 | vs | Hampton | 20 | Detroit MI | |||
| 9/10/2005 | Hampton | 22 | @ | Howard | 12 | MEAC | |||
| 9/15/2005 | Hampton | 23 | @ | NC A&T | 14 | MEAC | |||
| 9/24/2005 | Hampton | 44 | vs | Morgan St | 14 | MEAC | East Rutherford NJ | ||
| 10/1/2005 | Delaware St | 8 | @ | Hampton | 26 | MEAC | |||
| 10/8/2005 | Hampton | 52 | @ | Gardner Webb | 21 | ||||
| 10/15/2005 | Hampton | 55 | @ | Norfolk St | 14 | MEAC | |||
| 10/22/2005 | S Carolina St | 10 | @ | Hampton | 14 | MEAC | |||
| 11/5/2005 | Hampton | 24 | @ | Bethune-Cookman | 10 | MEAC | |||
| 11/12/2005 | Florida A&M | 14 | @ | Hampton | 34 | MEAC | |||
| 11/19/2005 | Savannah St | 6 | @ | Hampton | 44 |